LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN
91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2015-08-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/68 |
| _version_ | 1797881872334716928 |
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| author | V. B. Denisenko E. N. Simovanyan |
| author_facet | V. B. Denisenko E. N. Simovanyan |
| author_sort | V. B. Denisenko |
| collection | DOAJ |
| description | 91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression in children were HIV blood viral load 300 000 cop./ml and CD4+-lymphocytes count 20% in the age of six months. The use of HIV blood viral load level as a prognostic test is preferred because of higher sensitivity (91,3%) and specificity (97,1%). |
| first_indexed | 2024-04-10T03:26:59Z |
| format | Article |
| id | doaj.art-ddaadffe505d4e058922c1d38dc7ea6b |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2024-04-10T03:26:59Z |
| publishDate | 2015-08-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-ddaadffe505d4e058922c1d38dc7ea6b2023-03-13T07:28:21ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-0112181110.22627/2072-8107-2013-12-1-8-1168LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDRENV. B. Denisenko0E. N. Simovanyan1Ростовский государственный медицинский университет, Ростов-на-ДонуРостовский государственный медицинский университет, Ростов-на-Дону91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression in children were HIV blood viral load 300 000 cop./ml and CD4+-lymphocytes count 20% in the age of six months. The use of HIV blood viral load level as a prognostic test is preferred because of higher sensitivity (91,3%) and specificity (97,1%).https://detinf.elpub.ru/jour/article/view/68вич-инфекциядетипредикторы быстрого прогрессирования |
| spellingShingle | V. B. Denisenko E. N. Simovanyan LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN Детские инфекции (Москва) вич-инфекция дети предикторы быстрого прогрессирования |
| title | LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN |
| title_full | LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN |
| title_fullStr | LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN |
| title_full_unstemmed | LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN |
| title_short | LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN |
| title_sort | laboratory predictors of rapid hiv development in children |
| topic | вич-инфекция дети предикторы быстрого прогрессирования |
| url | https://detinf.elpub.ru/jour/article/view/68 |
| work_keys_str_mv | AT vbdenisenko laboratorypredictorsofrapidhivdevelopmentinchildren AT ensimovanyan laboratorypredictorsofrapidhivdevelopmentinchildren |