Clinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats

Clinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats

Objective: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.Methods: A total of 61 KOA patients were...

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Bibliographic Details
Main Authors: Ting Zhao, Shiqi Wang, Wenbin Liu, Jiayan Shen, Youwu Dai, Mingqin Shi, Xiaoyi Huang, Yuanyuan Wei, Tao Li, Xiaoyu Zhang, Zhaohu Xie, Na Wang, Dongdong Qin, Zhaofu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Genetics
Subjects:
knee osteoarthritis
YQYXF
clinical efficacy
metabolome
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1096616/full

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