Orally Fed Recombinant <i>Lactococcus lactis</i> Displaying Surface Anti-Fimbrial Nanobodies Protects Piglets against <i>Escherichia coli</i> Causing Post-Weaning Diarrhea

Orally Fed Recombinant <i>Lactococcus lactis</i> Displaying Surface Anti-Fimbrial Nanobodies Protects Piglets against <i>Escherichia coli</i> Causing Post-Weaning Diarrhea

Post-weaning diarrhea (PWD) and edema disease (ED), caused by enterotoxigenic and Shiga toxin producing <i>Escherichia coli</i> (ETEC and STEC) strains, are important diseases of newly weaned piglets worldwide. The objective of this study is to develop a passive immunization strategy to...

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Bibliographic Details
Main Authors: Emmanuel Okello, Kristof Moonens, Joseph Erume, Henri De Greve
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Agriculture
Subjects:
post-weaning diarrhea
edema diseases
ETEC
STEC
VHH
Nanobodies
Online Access:https://www.mdpi.com/2077-0472/11/3/186

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