Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report
Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is usually seen as a minor component in patients pres...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-02-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7238/15298_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal
carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is usually
seen as a minor component in patients presenting with mixed germ cell tumour. We report a rare case of 27-year-old Hepatitis C positive
male presenting with pain in left lower abdomen with associated history of same sided undescended testis and infertility. Right sided
testis lying in scrotal sac appeared normal on ultrasonography but patient was azoospermic. He had raised levels of serum markers,
alpha feto protein and beta HCG. Examination showed a large mass in left lower abdomen involving the sigmoid colon with the absence
of left testis in left scrotum which was confirmed on CT scan. Excision of the mass was done and histopathology examination revealed
it as a malignant mixed germ cell tumour composed predominantly of a yolk sac tumour, with minor component as seminoma and
embryonal carcinoma in an undescended testis. Following this, the level of serum markers came down. The patient is now undergoing
adjuvant chemotherapy and is doing well. |
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| ISSN: | 2249-782X 0973-709X |