Comprehensive and systematic characterization of multi-functionalized cisplatin nano-conjugate: from the chemistry and proteomic biocompatibility to the animal model

Comprehensive and systematic characterization of multi-functionalized cisplatin nano-conjugate: from the chemistry and proteomic biocompatibility to the animal model

Abstract Background Nowadays, nanoparticles (NPs) have evolved as multifunctional systems combining different custom anchorages which opens a wide range of applications in biomedical research. Thus, their pharmacological involvements require more comprehensive analysis and novel nanodrugs should be...

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Main Authors: Ángela-Patricia Hernández, Ania Micaelo, Rafael Piñol, Marina L. García-Vaquero, José J. Aramayona, Julio J. Criado, Emilio Rodriguez, José Ignacio Sánchez-Gallego, Alicia Landeira-Viñuela, Pablo Juanes-Velasco, Paula Díez, Rafael Góngora, Ricardo Jara-Acevedo, Alberto Orfao, Javier Miana-Mena, María Jesús Muñoz, Sergio Villanueva, Ángel Millán, Manuel Fuentes
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Nanobiotechnology
Subjects:
Nanoparticles
Cisplatin
Iron oxide nanoparticles
Protein corona
Drug delivery
Biocompatibility
Online Access:https://doi.org/10.1186/s12951-022-01546-y

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