Heterocycles [h]-Fused Onto 4-Oxoquinoline-3-Carboxylic Acid, Part VIII [1]. Convenient Synthesis and Antimicrobial Properties of Substituted Hexahydro[1,4]diazepino[2,3-h]quinoline-9-carboxylic acid and Its Tetrahydroquino[7,8-b]benzodiazepine Analog

Heterocycles [h]-Fused Onto 4-Oxoquinoline-3-Carboxylic Acid, Part VIII [1]. Convenient Synthesis and Antimicrobial Properties of Substituted Hexahydro[1,4]diazepino[2,3-h]quinoline-9-carboxylic acid and Its Tetrahydroquino[7,8-b]benzodiazepine Analog

[1,4]Diazepino[2,3-h]quinolone carboxylic acid 3 and its benzo-homolog tetrahydroquino[7,8-b]benzodiazepine-3-carboxylic acid 5 were prepared via PPAcatalyzed thermal lactamization of the respective 8-amino-7-substituted-1,4-dihydroquinoline-3-carboxylic acid derivatives 8, 10. The latter compounds...

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Bibliographic Details
Main Authors: Yusuf M. Al-Hiari, Rana Abu-Dahab, Mustafa M. El-Abadelah
Format: Article
Language:English
Published: MDPI AG 2008-11-01
Series:Molecules
Subjects:
7-Chloro-8-nitro-4-oxoquinoline-3-carboxylic acid
β-alanine
diazepino[2
3- h]quinoline
2-aminobenzoic acid
quino[7
8-b]benzodiazepine
SN-Ar reaction
antibacterial activity
Online Access:http://www.mdpi.com/1420-3049/13/11/2880/

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