High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis

Current DNA computational systems are constrained by integration efficiency, device structures and limited functions. Here the authors design a DNA arithmetic logic unit that uses polymerase-mediated strand displacement.

Bibliographic Details
Main Authors: Haomiao Su, Jinglei Xu, Qi Wang, Fuan Wang, Xiang Zhou
Format: Article
Language:English
Published: Nature Portfolio 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13310-2
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author Haomiao Su
Jinglei Xu
Qi Wang
Fuan Wang
Xiang Zhou
author_facet Haomiao Su
Jinglei Xu
Qi Wang
Fuan Wang
Xiang Zhou
author_sort Haomiao Su
collection DOAJ
description Current DNA computational systems are constrained by integration efficiency, device structures and limited functions. Here the authors design a DNA arithmetic logic unit that uses polymerase-mediated strand displacement.
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issn 2041-1723
language English
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spelling doaj.art-ddb761ba189449df9990667450e3027b2022-12-21T23:38:59ZengNature PortfolioNature Communications2041-17232019-11-011011810.1038/s41467-019-13310-2High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesisHaomiao Su0Jinglei Xu1Qi Wang2Fuan Wang3Xiang Zhou4Key Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan UniversityKey Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan UniversityKey Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan UniversityKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan UniversityKey Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan UniversityCurrent DNA computational systems are constrained by integration efficiency, device structures and limited functions. Here the authors design a DNA arithmetic logic unit that uses polymerase-mediated strand displacement.https://doi.org/10.1038/s41467-019-13310-2
spellingShingle Haomiao Su
Jinglei Xu
Qi Wang
Fuan Wang
Xiang Zhou
High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
Nature Communications
title High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
title_full High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
title_fullStr High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
title_full_unstemmed High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
title_short High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis
title_sort high efficiency and integrable dna arithmetic and logic system based on strand displacement synthesis
url https://doi.org/10.1038/s41467-019-13310-2
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AT qiwang highefficiencyandintegrablednaarithmeticandlogicsystembasedonstranddisplacementsynthesis
AT fuanwang highefficiencyandintegrablednaarithmeticandlogicsystembasedonstranddisplacementsynthesis
AT xiangzhou highefficiencyandintegrablednaarithmeticandlogicsystembasedonstranddisplacementsynthesis