<i>MTHFR</i> c.665C>T and c.1298A>C Polymorphisms in Tailoring Personalized Anti-TNF-α Therapy for Rheumatoid Arthritis

<i>MTHFR</i> c.665C>T and c.1298A>C Polymorphisms in Tailoring Personalized Anti-TNF-α Therapy for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 1%. Currently, RA treatment aims to achieve low disease activity or remission. Failure to achieve this goal causes disease progression with a poor prognosis. When treatment with first-line drugs fails, treatment wit...

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Bibliographic Details
Main Authors: Amin Ravaei, Lia Pulsatelli, Elisa Assirelli, Jacopo Ciaffi, Riccardo Meliconi, Carlo Salvarani, Marcello Govoni, Michele Rubini
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
TNF-α inhibitors
genetic association
<i>MTHFR</i>
biomarkers
pharmacogenetics
Online Access:https://www.mdpi.com/1422-0067/24/4/4110

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