Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District
Canine rabies causes an estimated 60,000 human deaths per year, but these deaths are preventable through post-exposure prophylaxis of people and vaccination of domestic dogs. Dog vaccination campaigns targeting 70% of the population are effective at interrupting transmission. Here, we report on less...
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| Format: | Article |
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MDPI AG
2021-04-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/6/2/48 |
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| author | Caitlynn Filla Malavika Rajeev Zoavina Randriana Chantal Hanitriniana Radoniaina R. Rafaliarison Glenn Torrencelli Edosoa Mamitiana Andriamananjara Nivohanitra P. Razafindraibe José Nely Angelique Ferreira Annie L. Yang Fenomanana Daniel Tara A. Clarke Zachary Farris Terry Stone Jochem Lastdrager Tsiky Rajaonarivelo Katie Hampson C. Jessica E. Metcalf Kim Valenta |
| author_facet | Caitlynn Filla Malavika Rajeev Zoavina Randriana Chantal Hanitriniana Radoniaina R. Rafaliarison Glenn Torrencelli Edosoa Mamitiana Andriamananjara Nivohanitra P. Razafindraibe José Nely Angelique Ferreira Annie L. Yang Fenomanana Daniel Tara A. Clarke Zachary Farris Terry Stone Jochem Lastdrager Tsiky Rajaonarivelo Katie Hampson C. Jessica E. Metcalf Kim Valenta |
| author_sort | Caitlynn Filla |
| collection | DOAJ |
| description | Canine rabies causes an estimated 60,000 human deaths per year, but these deaths are preventable through post-exposure prophylaxis of people and vaccination of domestic dogs. Dog vaccination campaigns targeting 70% of the population are effective at interrupting transmission. Here, we report on lessons learned during pilot dog vaccination campaigns in the Moramanga District of Madagascar. We compare two different vaccination strategies: a volunteer-driven effort to vaccinate dogs in two communes using static point vaccination and continuous vaccination as part of routine veterinary services. We used dog age data from the campaigns to estimate key demographic parameters and to simulate different vaccination strategies. Overall, we found that dog vaccination was feasible and that most dogs were accessible to vaccination. The static-point campaign achieved higher coverage but required more resources and had a limited geographic scope compared to the continuous delivery campaign. Our modeling results suggest that targeting puppies through community-based vaccination efforts could improve coverage. We found that mass dog vaccination is feasible and can achieve high coverage in Madagascar; however, context-specific strategies and an investment in dog vaccination as a public good will be required to move the country towards elimination. |
| first_indexed | 2024-03-10T12:23:37Z |
| format | Article |
| id | doaj.art-ddbab1f16d9b403a96cb4cdceab794d9 |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-10T12:23:37Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-ddbab1f16d9b403a96cb4cdceab794d92023-11-21T15:15:20ZengMDPI AGTropical Medicine and Infectious Disease2414-63662021-04-01624810.3390/tropicalmed6020048Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga DistrictCaitlynn Filla0Malavika Rajeev1Zoavina Randriana2Chantal Hanitriniana3Radoniaina R. Rafaliarison4Glenn Torrencelli Edosoa5Mamitiana Andriamananjara6Nivohanitra P. Razafindraibe7José Nely8Angelique Ferreira9Annie L. Yang10Fenomanana Daniel11Tara A. Clarke12Zachary Farris13Terry Stone14Jochem Lastdrager15Tsiky Rajaonarivelo16Katie Hampson17C. Jessica E. Metcalf18Kim Valenta19Department of Anthropology, University of Florida, Gainesville, FL 32611, USADepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USAThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarMention Zoologie et Biodiversité Animale, Faculté des Sciences, Université d’Antananarivo, Antananarivo 101, MadagascarThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarChargé des Maladies Tropicales Négligées Organisation Mondiale de la Santé Madagascar, Antananarivo 101, MadagascarDirection des Services Vétérinaires Ministère Chargé de l’Agriculture et de l’Élevage, Antananarivo 101, MadagascarDirection des Services Vétérinaires Ministère Chargé de l’Agriculture et de l’Élevage, Antananarivo 101, MadagascarService contre les Maladies Endémo-épidémiques et Tropicales Négligées Ministère de la Santé Publique, Antananarivo 101, MadagascarThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USAThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarTravelling Animal Doctors, Newark, DE 19711-2916, USATravelling Animal Doctors, Newark, DE 19711-2916, USAThe Mad Dog Initiative Akanin’ny Veterinera, Akaikiniarivo, Ambatobe, Antananarivo 101, MadagascarBoyd Orr Centre for Population and Ecosystem Health Institute of Biodiversity, Animal Health and Comparative Medicine University of Glasgow, Glasgow G12 8QQ, UKDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USADepartment of Anthropology, University of Florida, Gainesville, FL 32611, USACanine rabies causes an estimated 60,000 human deaths per year, but these deaths are preventable through post-exposure prophylaxis of people and vaccination of domestic dogs. Dog vaccination campaigns targeting 70% of the population are effective at interrupting transmission. Here, we report on lessons learned during pilot dog vaccination campaigns in the Moramanga District of Madagascar. We compare two different vaccination strategies: a volunteer-driven effort to vaccinate dogs in two communes using static point vaccination and continuous vaccination as part of routine veterinary services. We used dog age data from the campaigns to estimate key demographic parameters and to simulate different vaccination strategies. Overall, we found that dog vaccination was feasible and that most dogs were accessible to vaccination. The static-point campaign achieved higher coverage but required more resources and had a limited geographic scope compared to the continuous delivery campaign. Our modeling results suggest that targeting puppies through community-based vaccination efforts could improve coverage. We found that mass dog vaccination is feasible and can achieve high coverage in Madagascar; however, context-specific strategies and an investment in dog vaccination as a public good will be required to move the country towards elimination.https://www.mdpi.com/2414-6366/6/2/48canine rabiesmass dog vaccinationcentral point vaccinationpuppy vaccinationZeroby30 |
| spellingShingle | Caitlynn Filla Malavika Rajeev Zoavina Randriana Chantal Hanitriniana Radoniaina R. Rafaliarison Glenn Torrencelli Edosoa Mamitiana Andriamananjara Nivohanitra P. Razafindraibe José Nely Angelique Ferreira Annie L. Yang Fenomanana Daniel Tara A. Clarke Zachary Farris Terry Stone Jochem Lastdrager Tsiky Rajaonarivelo Katie Hampson C. Jessica E. Metcalf Kim Valenta Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District Tropical Medicine and Infectious Disease canine rabies mass dog vaccination central point vaccination puppy vaccination Zeroby30 |
| title | Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District |
| title_full | Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District |
| title_fullStr | Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District |
| title_full_unstemmed | Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District |
| title_short | Lessons Learned and Paths Forward for Rabies Dog Vaccination in Madagascar: A Case Study of Pilot Vaccination Campaigns in Moramanga District |
| title_sort | lessons learned and paths forward for rabies dog vaccination in madagascar a case study of pilot vaccination campaigns in moramanga district |
| topic | canine rabies mass dog vaccination central point vaccination puppy vaccination Zeroby30 |
| url | https://www.mdpi.com/2414-6366/6/2/48 |
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