“Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) occurs when fat accumulates in the liver even without excessive alcohol intake. Among the current therapeutic approaches for NAFLD, lifestyle modification with dietary changes and regular exercise is the mainstay treatment. With the rise of intestinal microe...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1050709/full |
| _version_ | 1811322007146463232 |
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| author | Kangxiao Guo Sisheng Xu Zhaofeng Zeng |
| author_facet | Kangxiao Guo Sisheng Xu Zhaofeng Zeng |
| author_sort | Kangxiao Guo |
| collection | DOAJ |
| description | Non-alcoholic fatty liver disease (NAFLD) occurs when fat accumulates in the liver even without excessive alcohol intake. Among the current therapeutic approaches for NAFLD, lifestyle modification with dietary changes and regular exercise is the mainstay treatment. With the rise of intestinal microecology, regulation of the “liver–gut” axis can be an effective treatment for NAFLD. This review aimed to assess the modulation of the liver–gut microbiota axis with traditional Chinese medicine (TCM) as a therapeutic approach to NAFLD and further explored its application in the newly discovered therapeutic avenues beyond NAFLD treatment. |
| first_indexed | 2024-04-13T13:27:36Z |
| format | Article |
| id | doaj.art-ddbc6894b5074c8faf99c814f217899b |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-13T13:27:36Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-ddbc6894b5074c8faf99c814f217899b2022-12-22T02:45:04ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-11-011310.3389/fendo.2022.10507091050709“Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver diseaseKangxiao GuoSisheng XuZhaofeng ZengNon-alcoholic fatty liver disease (NAFLD) occurs when fat accumulates in the liver even without excessive alcohol intake. Among the current therapeutic approaches for NAFLD, lifestyle modification with dietary changes and regular exercise is the mainstay treatment. With the rise of intestinal microecology, regulation of the “liver–gut” axis can be an effective treatment for NAFLD. This review aimed to assess the modulation of the liver–gut microbiota axis with traditional Chinese medicine (TCM) as a therapeutic approach to NAFLD and further explored its application in the newly discovered therapeutic avenues beyond NAFLD treatment.https://www.frontiersin.org/articles/10.3389/fendo.2022.1050709/full“liver–gut” axisintestinal microorganismstraditional Chinese medicineNAFLDtarget |
| spellingShingle | Kangxiao Guo Sisheng Xu Zhaofeng Zeng “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease Frontiers in Endocrinology “liver–gut” axis intestinal microorganisms traditional Chinese medicine NAFLD target |
| title | “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease |
| title_full | “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease |
| title_fullStr | “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease |
| title_full_unstemmed | “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease |
| title_short | “Liver–gut” axis: A target of traditional Chinese medicine for the treatment of non-alcoholic fatty liver disease |
| title_sort | liver gut axis a target of traditional chinese medicine for the treatment of non alcoholic fatty liver disease |
| topic | “liver–gut” axis intestinal microorganisms traditional Chinese medicine NAFLD target |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1050709/full |
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