The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle
Turkish Grey cattle (B. taurus) are the only native cattle breed of Türkiye"s Thrace and Western Anatolia regions. They can spend the whole year as free herds, including the hottest and coldest months, and can survive, feed, and reproduce without any human intervention. Therefore, Turkish Grey...
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| Format: | Article |
| Language: | English |
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Kafkas University, Faculty of Veterinary Medicine
2023-09-01
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| Series: | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://vetdergikafkas.org/pdf.php?id=3023 |
| _version_ | 1797403870122475520 |
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| author | Sertaç ATALAY Süleyman KÖK |
| author_facet | Sertaç ATALAY Süleyman KÖK |
| author_sort | Sertaç ATALAY |
| collection | DOAJ |
| description | Turkish Grey cattle (B. taurus) are the only native cattle breed of Türkiye"s Thrace and
Western Anatolia regions. They can spend the whole year as free herds, including the
hottest and coldest months, and can survive, feed, and reproduce without any human
intervention. Therefore, Turkish Grey cattle are of interest for genetic marker studies
on heat stress tolerance. This study was aimed to identify genetic polymorphism in the
DNA binding domain (DBD) encoding region of the heat shock transcription factor 1
(HSF1) gene in Holstein (n: 50) and Turkish Grey (n: 50) cattle. It was determined that
the 121 amino acid long sequence encoded by the first three exons of the HSF1 gene
was the same in Turkish Grey and Holstein cattle. Two intronic and one synonymous
SNPs were identified in Turkish Grey (rs719296338, rs522980029, rs17880386) and
one inronic SNP (rs17870386) in Holstein cattle by DNA sequencing. These SNPs were
searched in the Bovine Genome Variation Database (BGVD). Interestingly, according
to BGVD, rs522980029 was conserved in B. indicus but absent in B. taurus. Moreover,
the rs719296338 locus is monomorphic in western European and Eurasian taurine but
is polymorphic in East Asian taurines and B. indicus. The results support the view that
B. indicus is genetic introgression into B. taurus cattle in Anatolia. This hybridization
may have contributed to Turkish Grey cattle ability to adapt to harsh environmental
conditions and heat stress. |
| first_indexed | 2024-03-09T02:44:43Z |
| format | Article |
| id | doaj.art-ddbc9c1b0e04482cb76b91675c11658b |
| institution | Directory Open Access Journal |
| issn | 1309-2251 |
| language | English |
| last_indexed | 2024-03-09T02:44:43Z |
| publishDate | 2023-09-01 |
| publisher | Kafkas University, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| spelling | doaj.art-ddbc9c1b0e04482cb76b91675c11658b2023-12-05T21:27:24ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512023-09-0129542943510.9775/kvfd.2023.292563023The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattleSertaç ATALAY0Süleyman KÖK1Tekirdağ Namık Kemal University, Central Research Laboratory (NABILTEM), TR-59000 Tekirdağ - TÜRKİYETrakya University, Faculty of Engineering, Department of Genetics and Bioengineering, TR-22030 Edirne - TÜRKİYETurkish Grey cattle (B. taurus) are the only native cattle breed of Türkiye"s Thrace and Western Anatolia regions. They can spend the whole year as free herds, including the hottest and coldest months, and can survive, feed, and reproduce without any human intervention. Therefore, Turkish Grey cattle are of interest for genetic marker studies on heat stress tolerance. This study was aimed to identify genetic polymorphism in the DNA binding domain (DBD) encoding region of the heat shock transcription factor 1 (HSF1) gene in Holstein (n: 50) and Turkish Grey (n: 50) cattle. It was determined that the 121 amino acid long sequence encoded by the first three exons of the HSF1 gene was the same in Turkish Grey and Holstein cattle. Two intronic and one synonymous SNPs were identified in Turkish Grey (rs719296338, rs522980029, rs17880386) and one inronic SNP (rs17870386) in Holstein cattle by DNA sequencing. These SNPs were searched in the Bovine Genome Variation Database (BGVD). Interestingly, according to BGVD, rs522980029 was conserved in B. indicus but absent in B. taurus. Moreover, the rs719296338 locus is monomorphic in western European and Eurasian taurine but is polymorphic in East Asian taurines and B. indicus. The results support the view that B. indicus is genetic introgression into B. taurus cattle in Anatolia. This hybridization may have contributed to Turkish Grey cattle ability to adapt to harsh environmental conditions and heat stress.https://vetdergikafkas.org/pdf.php?id=3023genetic introgressiongrey cattleheat stress |
| spellingShingle | Sertaç ATALAY Süleyman KÖK The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle Kafkas Universitesi Veteriner Fakültesi Dergisi genetic introgression grey cattle heat stress |
| title | The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| title_full | The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| title_fullStr | The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| title_full_unstemmed | The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| title_short | The comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| title_sort | comparison of polymorphisms in the heat shock transcription factor 1 gene of turkish grey cattle and holstein cattle |
| topic | genetic introgression grey cattle heat stress |
| url | https://vetdergikafkas.org/pdf.php?id=3023 |
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