Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice
The nucleus accumbens (NAc) is involved in mediating reward seeking and negative valence. Here, the authors present evidence for afferent-specific circuitry of the NAc in the control of reward and aversion via two distinct pathway.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33843-3 |
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author | Kuikui Zhou Hua Xu Shanshan Lu Shaolei Jiang Guoqiang Hou Xiaofei Deng Miao He Yingjie Zhu |
author_facet | Kuikui Zhou Hua Xu Shanshan Lu Shaolei Jiang Guoqiang Hou Xiaofei Deng Miao He Yingjie Zhu |
author_sort | Kuikui Zhou |
collection | DOAJ |
description | The nucleus accumbens (NAc) is involved in mediating reward seeking and negative valence. Here, the authors present evidence for afferent-specific circuitry of the NAc in the control of reward and aversion via two distinct pathway. |
first_indexed | 2024-04-13T17:39:10Z |
format | Article |
id | doaj.art-ddbcd223fc9f41baa829ef09bab46de5 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-13T17:39:10Z |
publishDate | 2022-10-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-ddbcd223fc9f41baa829ef09bab46de52022-12-22T02:37:14ZengNature PortfolioNature Communications2041-17232022-10-0113111210.1038/s41467-022-33843-3Reward and aversion processing by input-defined parallel nucleus accumbens circuits in miceKuikui Zhou0Hua Xu1Shanshan Lu2Shaolei Jiang3Guoqiang Hou4Xiaofei Deng5Miao He6Yingjie Zhu7Shenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsInstitutes of Brain Science, Department of Neurology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan UniversityShenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsThe nucleus accumbens (NAc) is involved in mediating reward seeking and negative valence. Here, the authors present evidence for afferent-specific circuitry of the NAc in the control of reward and aversion via two distinct pathway.https://doi.org/10.1038/s41467-022-33843-3 |
spellingShingle | Kuikui Zhou Hua Xu Shanshan Lu Shaolei Jiang Guoqiang Hou Xiaofei Deng Miao He Yingjie Zhu Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice Nature Communications |
title | Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice |
title_full | Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice |
title_fullStr | Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice |
title_full_unstemmed | Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice |
title_short | Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice |
title_sort | reward and aversion processing by input defined parallel nucleus accumbens circuits in mice |
url | https://doi.org/10.1038/s41467-022-33843-3 |
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