Viral Vectors Applied for RNAi-Based Antiviral Therapy

Viral Vectors Applied for RNAi-Based Antiviral Therapy

RNA interference (RNAi) provides the means for alternative antiviral therapy. Delivery of RNAi in the form of short interfering RNA (siRNA), short hairpin RNA (shRNA) and micro-RNA (miRNA) have demonstrated efficacy in gene silencing for therapeutic applications against viral diseases. Bioinformatic...

Full description

Bibliographic Details
Main Author:	Kenneth Lundstrom
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Viruses
Subjects:	RNA interference shRNA siRNA miRNA gene silencing viral vectors
Online Access:	https://www.mdpi.com/1999-4915/12/9/924

Similar Items

Are Viral Vectors Any Good for RNAi Antiviral Therapy?
by: Kenneth Lundstrom
Published: (2020-10-01)

Advances with RNAi-Based Therapy for Hepatitis B Virus Infection
by: Fiona van den Berg, et al.
Published: (2020-08-01)

7.346 RNAi: A Revolution in Biology and Therapeutics, Spring 2010
by: Gurtan, Allan, et al.
Published: (2023)

Basic Principles of RNA Interference: Nucleic Acid Types and In Vitro Intracellular Delivery Methods
by: Marie Isenmann, et al.
Published: (2023-06-01)

RNA Interference as a Prospective Tool for the Control of Human Viral Infections
by: Alesia Levanova, et al.
Published: (2018-09-01)

Combinational treatments of RNA interference and extracellular vesicles in the spinocerebellar ataxia
by: Yingying Ding, et al.
Published: (2022-10-01)

SSD - a free software for designing multimeric mono-, bi- and trivalent shRNAs
by: Gabriel José de Carli, et al.
Published: (2020-03-01)

Right on target: The next class of efficient, safe, and specific RNAi triggers
by: Jonas Becker, et al.
Published: (2022-06-01)

Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside
by: Yingshan Qiu, et al.
Published: (2016-09-01)

RISC-y Business: Limitations of Short Hairpin RNA-Mediated Gene Silencing in the Brain and a Discussion of CRISPR/Cas-Based Alternatives
by: Kanishk Goel, et al.
Published: (2022-07-01)

Multiplexed shRNA-miRs as a candidate for anti HIV-1 therapy: strategies, challenges, and future potential
by: Jyotsna Jai, et al.
Published: (2022-12-01)

RNAi-Based Approaches for Pancreatic Cancer Therapy
by: Min Ju Kim, et al.
Published: (2021-10-01)

Nanoliposomes as nonviral vectors in cancer gene therapy
by: Safiye Nur Yildiz, et al.
Published: (2024-07-01)

Current strategies employed in the manipulation of gene expression for clinical purposes
by: Hsing-Chuan Tsai, et al.
Published: (2022-11-01)

RNAi mechanisms in Huntington’s disease therapy: siRNA versus shRNA
by: Sebastian Aguiar, et al.
Published: (2017-11-01)

Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers
by: Md. Emranul Karim, et al.
Published: (2018-05-01)

Delivery of RNAi-Based Oligonucleotides by Electropermeabilization
by: Muriel Golzio, et al.
Published: (2013-04-01)

Manipulation of plant host susceptibility: an emerging role for viral movement proteins?
by: Khalid eAmari, et al.
Published: (2012-01-01)

Nanoparticles as Drug Delivery Systems in Cancer Medicine: Emphasis on RNAi-Containing Nanoliposomes
by: Pablo E. Vivas-Mejia, et al.
Published: (2013-11-01)

Recent Findings Concerning PAMAM Dendrimer Conjugates with Cyclodextrins as Carriers of DNA and RNA
by: Keiichi Motoyama, et al.
Published: (2009-08-01)

Optimization of Synthesis of the Amino Lipid ECO for Effective Delivery of Nucleic Acids
by: Andrew L. Schilb, et al.
Published: (2021-10-01)

Nano-based delivery of RNAi in cancer therapy
by: Yong Xin, et al.
Published: (2017-07-01)

Reprogramming tendon healing: a guide to novel molecular tools
by: Carlos Julio Peniche Silva, et al.
Published: (2024-05-01)

RNA interference: more than a research tool in the vertebrates' adaptive immunity
by: Mak Johnson
Published: (2005-05-01)

Evaluation of RNA Secondary Stem-Loop Structures in the UTRs of Mouse Hepatitis Virus as New Therapeutic Targets
by: Gyuhyun Kang, et al.
Published: (2024-06-01)

Small Interfering RNAs Are Highly Effective Inhibitors of Crimean-Congo Hemorrhagic Fever Virus Replication In Vitro
by: Fanni Földes, et al.
Published: (2020-12-01)

RNA interference approaches for plant disease control
by: Yen-Wen Kuo, et al.
Published: (2020-12-01)

Anti-<i>c-myc</i> RNAi-Based Onconanotherapeutics
by: Saffiya Habib, et al.
Published: (2020-12-01)

Protein-mediated miRNA detection and siRNA enrichment using p19
by: Jingmin Jin, et al.
Published: (2010-06-01)

Tetrazine-Induced Bioorthogonal Activation of Vitamin E-Modified siRNA for Gene Silencing
by: Xueli Zhang, et al.
Published: (2022-07-01)

Limitations of Clinical Application of siRNA Delivery Based on Non-Viral Vectors
by: Reza Ghavimi, et al.
Published: (2014-04-01)

Aptamer-iRNAs as Therapeutics for Cancer Treatment
by: Mario M. Soldevilla, et al.
Published: (2018-10-01)

Promising Directions in Atherosclerosis Treatment Based on Epigenetic Regulation Using MicroRNAs and Long Noncoding RNAs
by: Daria Skuratovskaia, et al.
Published: (2019-06-01)

Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA
by: Hidetoshi Arima, et al.
Published: (2012-02-01)

Using RNAi in the treatment of cardiovascular diseases - therapeutics based on siRNA overview
by: Barbara Rusinowska
Published: (2022-08-01)

Harnessing Intronic microRNA Structures to Improve Tolerance and Expression of shRNAs in Animal Cells
by: Arjun Challagulla, et al.
Published: (2022-02-01)

Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA
by: Riai Okamoto, et al.
Published: (2023-09-01)

The Role of RNA Interference (RNAi) in Arbovirus-Vector Interactions
by: Carol D. Blair, et al.
Published: (2015-02-01)

DisCoVering potential candidates of RNAi-based therapy for COVID-19 using computational methods
by: Narjes Rohani, et al.
Published: (2021-02-01)

Concepts and considerations for enhancing RNAi efficiency in phytopathogenic fungi for RNAi-based crop protection using nanocarrier-mediated dsRNA delivery systems
by: Poonam Ray, et al.
Published: (2022-09-01)