Hypoxia‐induced secretion stimulates breast cancer stem cell regulatory signalling pathways

Hypoxia‐induced secretion stimulates breast cancer stem cell regulatory signalling pathways

It is well known that tumour cells are dependent on communication with the tumour microenvironment. Previously, it has been shown that hypoxia (HX) induces pronounced, diverse and direct effects on cancer stem cell (CSC) qualities in different breast cancer subtypes. Here, we describe the mechanism...

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Bibliographic Details
Main Authors: Hanna Jacobsson, Hannah Harrison, Éamon Hughes, Emma Persson, Sara Rhost, Paul Fitzpatrick, Anna Gustafsson, Daniel Andersson, Pernilla Gregersson, Ylva Magnusson, Anders Ståhlberg, Göran Landberg
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Oncology
Subjects:
breast cancer
cancer stem cells
hypoxia
IL‐12
IL6
JAK‐STAT
Online Access:https://doi.org/10.1002/1878-0261.12500

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