Neuronal MHC-I complex is destabilized by amyloid-β and its implications in Alzheimer’s disease
Abstract Backgrounds The expression of major histocompatibility complex I (MHC-I) in neurons has recently been shown to regulate neurite outgrowth and synaptic plasticity. However, its contribution to neurodegenerative diseases such as Alzheimer's disease (AD) remains largely unknown. Methods I...
| Главные авторы: | , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
BMC
2023-09-01
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| Серии: | Cell & Bioscience |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1186/s13578-023-01132-1 |