Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran
Background: The aim of this study was to evaluate different concentrations of deltamethrin combined with formulated piperonyl butoxide (PBO) synergist on various surfaces against the wild strain of Anopheles stephensi, the main malaria vector in Southern Iran under semi-field condition. Methods: Fou...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-12-01
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| Series: | Journal of Arthropod-Borne Diseases |
| Subjects: | |
| Online Access: | https://jad.tums.ac.ir/index.php/jad/article/view/772 |
| _version_ | 1828745795232333824 |
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| author | Fatemeh Nikpour Hassan Vatandoost Ahmad Ali Hanafi-Bojd Ahmad Raeisi Mansour Ranjbar Ahmad Ali Enayati Mohammad Reza Abai Mansoreh Shayeghi Abdol Rasoul Mojahedi Abolghasem Pourreza |
| author_facet | Fatemeh Nikpour Hassan Vatandoost Ahmad Ali Hanafi-Bojd Ahmad Raeisi Mansour Ranjbar Ahmad Ali Enayati Mohammad Reza Abai Mansoreh Shayeghi Abdol Rasoul Mojahedi Abolghasem Pourreza |
| author_sort | Fatemeh Nikpour |
| collection | DOAJ |
| description | Background: The aim of this study was to evaluate different concentrations of deltamethrin combined with formulated piperonyl butoxide (PBO) synergist on various surfaces against the wild strain of Anopheles stephensi, the main malaria vector in Southern Iran under semi-field condition.
Methods: Four concentrations of deltamethrin WG 25% (Tagros) and PBO 800EC-UV (Endura) were prepared and sprayed on the pre-designed surfaces in accordance with WHO alliance line of the IRS Micronair®. The WHO’s recommended bioassay kit and method was used during this study.
Results: Comparing the mortality rate of mosquitoes, the results showed a significant difference between months after treatment of IRS (Indoor Residual Spraying) (P< 0.05) but didn’t show any significant differences between days during the first and second months (P> 0.05).Statistical test revealed a significance difference between mortality rate of mosquitoes in exposing to concentrations of 1 and 4 (P< 0.05) which demonstrated effect of synergizing PBO on mortality rate.
Conclusion: This research as the first semi-field trial on deltamethrin added to different concentrations of formulated PBO for IRS, indicates that deltamethrin+10X PBO is more effective than other concentrations. Therefore, using synergists can be suggested as a new tool for prevention of pyrethriod resistance, although more studies are recommended. |
| first_indexed | 2024-04-14T04:11:11Z |
| format | Article |
| id | doaj.art-ddc2689872f64349818a3dc369750e09 |
| institution | Directory Open Access Journal |
| issn | 1735-7179 2322-2271 |
| language | English |
| last_indexed | 2024-04-14T04:11:11Z |
| publishDate | 2017-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Arthropod-Borne Diseases |
| spelling | doaj.art-ddc2689872f64349818a3dc369750e092022-12-22T02:13:11ZengTehran University of Medical SciencesJournal of Arthropod-Borne Diseases1735-71792322-22712017-12-01114361Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in IranFatemeh Nikpour0Hassan Vatandoost1Ahmad Ali Hanafi-Bojd2Ahmad Raeisi3Mansour Ranjbar4Ahmad Ali Enayati5Mohammad Reza Abai6Mansoreh Shayeghi7Abdol Rasoul Mojahedi8Abolghasem Pourreza9Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Department of Environmental Chemical Pollutants, Institute for Environmental Research, Tehran Univer-sity of Medical Sciences, Tehran, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Department of Environmental Chemical Pollutants, Institute for Environmental Research, Tehran Univer-sity of Medical Sciences, Tehran, IranMalaria Control Department, Ministry of Health and Medical Education, Tehran, IranIndependent Malaria Consultant, Tehran, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Department of Environmental Chemical Pollutants, Institute for Environmental Research, Tehran Univer-sity of Medical Sciences, Tehran, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, IranProvincial Health Center, Bandar Abbas University of Medical Sciences, Bandar Abbas, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, IranBackground: The aim of this study was to evaluate different concentrations of deltamethrin combined with formulated piperonyl butoxide (PBO) synergist on various surfaces against the wild strain of Anopheles stephensi, the main malaria vector in Southern Iran under semi-field condition. Methods: Four concentrations of deltamethrin WG 25% (Tagros) and PBO 800EC-UV (Endura) were prepared and sprayed on the pre-designed surfaces in accordance with WHO alliance line of the IRS Micronair®. The WHO’s recommended bioassay kit and method was used during this study. Results: Comparing the mortality rate of mosquitoes, the results showed a significant difference between months after treatment of IRS (Indoor Residual Spraying) (P< 0.05) but didn’t show any significant differences between days during the first and second months (P> 0.05).Statistical test revealed a significance difference between mortality rate of mosquitoes in exposing to concentrations of 1 and 4 (P< 0.05) which demonstrated effect of synergizing PBO on mortality rate. Conclusion: This research as the first semi-field trial on deltamethrin added to different concentrations of formulated PBO for IRS, indicates that deltamethrin+10X PBO is more effective than other concentrations. Therefore, using synergists can be suggested as a new tool for prevention of pyrethriod resistance, although more studies are recommended.https://jad.tums.ac.ir/index.php/jad/article/view/772Insecticide resistanceAnopheles stephensiDeltamethrinPiperonyl butoxideIRS |
| spellingShingle | Fatemeh Nikpour Hassan Vatandoost Ahmad Ali Hanafi-Bojd Ahmad Raeisi Mansour Ranjbar Ahmad Ali Enayati Mohammad Reza Abai Mansoreh Shayeghi Abdol Rasoul Mojahedi Abolghasem Pourreza Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran Journal of Arthropod-Borne Diseases Insecticide resistance Anopheles stephensi Deltamethrin Piperonyl butoxide IRS |
| title | Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran |
| title_full | Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran |
| title_fullStr | Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran |
| title_full_unstemmed | Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran |
| title_short | Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran |
| title_sort | evaluation of deltamethrin in combination of piperonyl butoxide pbo against pyrethroid resistant malaria vector anopheles stephensi in irs implementation an experimental semi filed trial in iran |
| topic | Insecticide resistance Anopheles stephensi Deltamethrin Piperonyl butoxide IRS |
| url | https://jad.tums.ac.ir/index.php/jad/article/view/772 |
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