Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy
Abstract Background Enhanced recovery after surgery (ERAS) is a perioperative management protocol to accelerate patient recovery. This study aimed to evaluate the feasibility of ERAS protocols implemented in patients who underwent neoadjuvant chemotherapy (NACT) before minimally invasive McKeown eso...
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12957-022-02701-3 |
| _version_ | 1811222892542689280 |
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| author | Zhanpeng Tang Xirui Zhu Yanzhi Li Chenghao Qu Lin Li Shuhai Li Lei Qi Ming Lu Chuanle Cheng Hui Tian |
| author_facet | Zhanpeng Tang Xirui Zhu Yanzhi Li Chenghao Qu Lin Li Shuhai Li Lei Qi Ming Lu Chuanle Cheng Hui Tian |
| author_sort | Zhanpeng Tang |
| collection | DOAJ |
| description | Abstract Background Enhanced recovery after surgery (ERAS) is a perioperative management protocol to accelerate patient recovery. This study aimed to evaluate the feasibility of ERAS protocols implemented in patients who underwent neoadjuvant chemotherapy (NACT) before minimally invasive McKeown esophagectomy. Methods This retrospective study compared the short-term clinical outcomes in esophagectomy patients from June 2018 to June 2021. Subjects were divided into two categories: those who underwent NACT (NACT group) and the non-NACT group. Results There was no significant difference in total postoperative complication morbidity between the NACT and non-NACT groups (21.2% vs. 20.7%, P=0.936). In addition, the hospital length of stay post-surgery (7.90 vs. 7.71 days, P=0.424) was not significantly longer when compared to the non-NACT group. The time to chest tube removal (5.37 vs. 5.13 days, P=0.238) and first bowel movement (2.92 vs. 3.01 days, P=0.560) was also similar between the two groups. Conclusions There was no significant difference in postoperative complications rate, postoperative hospital length of stay, and readmission rate between the two group. This study proved that ERAS protocols seemed to be safe and feasible for patients who received NACT before esophagectomy. |
| first_indexed | 2024-04-12T08:23:42Z |
| format | Article |
| id | doaj.art-ddc6066d486243a3877cef491964c391 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-12T08:23:42Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-ddc6066d486243a3877cef491964c3912022-12-22T03:40:30ZengBMCWorld Journal of Surgical Oncology1477-78192022-07-012011910.1186/s12957-022-02701-3Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapyZhanpeng Tang0Xirui Zhu1Yanzhi Li2Chenghao Qu3Lin Li4Shuhai Li5Lei Qi6Ming Lu7Chuanle Cheng8Hui Tian9Department of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityDepartment of Thoracic Surgery, Qilu Hospital of Shandong UniversityAbstract Background Enhanced recovery after surgery (ERAS) is a perioperative management protocol to accelerate patient recovery. This study aimed to evaluate the feasibility of ERAS protocols implemented in patients who underwent neoadjuvant chemotherapy (NACT) before minimally invasive McKeown esophagectomy. Methods This retrospective study compared the short-term clinical outcomes in esophagectomy patients from June 2018 to June 2021. Subjects were divided into two categories: those who underwent NACT (NACT group) and the non-NACT group. Results There was no significant difference in total postoperative complication morbidity between the NACT and non-NACT groups (21.2% vs. 20.7%, P=0.936). In addition, the hospital length of stay post-surgery (7.90 vs. 7.71 days, P=0.424) was not significantly longer when compared to the non-NACT group. The time to chest tube removal (5.37 vs. 5.13 days, P=0.238) and first bowel movement (2.92 vs. 3.01 days, P=0.560) was also similar between the two groups. Conclusions There was no significant difference in postoperative complications rate, postoperative hospital length of stay, and readmission rate between the two group. This study proved that ERAS protocols seemed to be safe and feasible for patients who received NACT before esophagectomy.https://doi.org/10.1186/s12957-022-02701-3Enhanced recovery after surgery (ERAS)Neoadjuvant chemotherapyEsophagectomyEsophageal squamous cell carcinoma (ESCC) |
| spellingShingle | Zhanpeng Tang Xirui Zhu Yanzhi Li Chenghao Qu Lin Li Shuhai Li Lei Qi Ming Lu Chuanle Cheng Hui Tian Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy World Journal of Surgical Oncology Enhanced recovery after surgery (ERAS) Neoadjuvant chemotherapy Esophagectomy Esophageal squamous cell carcinoma (ESCC) |
| title | Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| title_full | Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| title_fullStr | Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| title_full_unstemmed | Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| title_short | Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| title_sort | feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy |
| topic | Enhanced recovery after surgery (ERAS) Neoadjuvant chemotherapy Esophagectomy Esophageal squamous cell carcinoma (ESCC) |
| url | https://doi.org/10.1186/s12957-022-02701-3 |
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