pH and Acid Base
Abstract This module integrates pH and acid-base concepts from basic lectures and readings with clinical information to enhance definitive patient care clinical decision making through team-based learning (TBL). The Henderson-Hasselbalch equation is used to apply the logarithmic pH function of hydro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Association of American Medical Colleges
2011-12-01
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| Series: | MedEdPORTAL |
| Subjects: | |
| Online Access: | http://www.mededportal.org/doi/10.15766/mep_2374-8265.8466 |
| _version_ | 1818580924836610048 |
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| author | Gary Onady Nicholas Reo Lawrance Prochaska |
| author_facet | Gary Onady Nicholas Reo Lawrance Prochaska |
| author_sort | Gary Onady |
| collection | DOAJ |
| description | Abstract This module integrates pH and acid-base concepts from basic lectures and readings with clinical information to enhance definitive patient care clinical decision making through team-based learning (TBL). The Henderson-Hasselbalch equation is used to apply the logarithmic pH function of hydrogen ion [H+] for calculating acid and base effects on proteins as a major theme behind this module. This task is accomplished by working through a problem set involving a premature infant recently diagnosed with Cystic Fibrosis, and the acid-base complications encountered as a result of this patient's unique disease process. Amino acid R groups that function as weak acids or bases during enzymatic protein digestion are identified and detailed as related to described mechanisms involved in general acid-base catalysis. Relevant information is then used to discriminate therapeutic interventions from the disease concepts identified. Since introducing this module, class performance on formal written exams related to pH and acid-base has improved over previous years before this module was incorporated. The students did have some interesting methods of connecting the data points from Applications Question 5. I noted zig zag lines and curvilinear lines used by some teams during the session. It may be worthwhile to note that the data points come with error ranges, so the best fit for a line averaging these points may be considered. |
| first_indexed | 2024-12-16T07:25:20Z |
| format | Article |
| id | doaj.art-ddc7432f0b224748a7e6f99296282286 |
| institution | Directory Open Access Journal |
| issn | 2374-8265 |
| language | English |
| last_indexed | 2024-12-16T07:25:20Z |
| publishDate | 2011-12-01 |
| publisher | Association of American Medical Colleges |
| record_format | Article |
| series | MedEdPORTAL |
| spelling | doaj.art-ddc7432f0b224748a7e6f992962822862022-12-21T22:39:31ZengAssociation of American Medical CollegesMedEdPORTAL2374-82652011-12-01710.15766/mep_2374-8265.8466pH and Acid BaseGary Onady0Nicholas Reo1Lawrance Prochaska21 Wright State University Boonshoft School of Medicine2 Wright State University3 Wright State UniversityAbstract This module integrates pH and acid-base concepts from basic lectures and readings with clinical information to enhance definitive patient care clinical decision making through team-based learning (TBL). The Henderson-Hasselbalch equation is used to apply the logarithmic pH function of hydrogen ion [H+] for calculating acid and base effects on proteins as a major theme behind this module. This task is accomplished by working through a problem set involving a premature infant recently diagnosed with Cystic Fibrosis, and the acid-base complications encountered as a result of this patient's unique disease process. Amino acid R groups that function as weak acids or bases during enzymatic protein digestion are identified and detailed as related to described mechanisms involved in general acid-base catalysis. Relevant information is then used to discriminate therapeutic interventions from the disease concepts identified. Since introducing this module, class performance on formal written exams related to pH and acid-base has improved over previous years before this module was incorporated. The students did have some interesting methods of connecting the data points from Applications Question 5. I noted zig zag lines and curvilinear lines used by some teams during the session. It may be worthwhile to note that the data points come with error ranges, so the best fit for a line averaging these points may be considered.http://www.mededportal.org/doi/10.15766/mep_2374-8265.8466TBLTeam-based LearningCystic FibrosisAmino AcidHenderson-Hasselbalch EquationPH |
| spellingShingle | Gary Onady Nicholas Reo Lawrance Prochaska pH and Acid Base MedEdPORTAL TBL Team-based Learning Cystic Fibrosis Amino Acid Henderson-Hasselbalch Equation PH |
| title | pH and Acid Base |
| title_full | pH and Acid Base |
| title_fullStr | pH and Acid Base |
| title_full_unstemmed | pH and Acid Base |
| title_short | pH and Acid Base |
| title_sort | ph and acid base |
| topic | TBL Team-based Learning Cystic Fibrosis Amino Acid Henderson-Hasselbalch Equation PH |
| url | http://www.mededportal.org/doi/10.15766/mep_2374-8265.8466 |
| work_keys_str_mv | AT garyonady phandacidbase AT nicholasreo phandacidbase AT lawranceprochaska phandacidbase |