Accelerating cancer without mutations

Mice get melanoma faster when they have common, inherited variants in a few genes that control cell-wide changes but also respond to the environment.

Bibliographic Details
Main Author: Douglas E Brash
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/45809
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author Douglas E Brash
author_facet Douglas E Brash
author_sort Douglas E Brash
collection DOAJ
description Mice get melanoma faster when they have common, inherited variants in a few genes that control cell-wide changes but also respond to the environment.
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spelling doaj.art-ddc8c86074de4eb49b038de49d492f022022-12-22T04:32:40ZengeLife Sciences Publications LtdeLife2050-084X2019-03-01810.7554/eLife.45809Accelerating cancer without mutationsDouglas E Brash0https://orcid.org/0000-0001-7437-9373Department of Therapeutic Radiology, Yale School of Medicine, New Haven, United States; Department of Dermatology, Yale School of Medicine, New Haven, United States; Yale Cancer Center, Yale School of Medicine, New Haven, United StatesMice get melanoma faster when they have common, inherited variants in a few genes that control cell-wide changes but also respond to the environment.https://elifesciences.org/articles/45809ultraviolet radiationmelanomamodifier genescancerribosomesRNA-binding protein
spellingShingle Douglas E Brash
Accelerating cancer without mutations
eLife
ultraviolet radiation
melanoma
modifier genes
cancer
ribosomes
RNA-binding protein
title Accelerating cancer without mutations
title_full Accelerating cancer without mutations
title_fullStr Accelerating cancer without mutations
title_full_unstemmed Accelerating cancer without mutations
title_short Accelerating cancer without mutations
title_sort accelerating cancer without mutations
topic ultraviolet radiation
melanoma
modifier genes
cancer
ribosomes
RNA-binding protein
url https://elifesciences.org/articles/45809
work_keys_str_mv AT douglasebrash acceleratingcancerwithoutmutations