Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers

Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers

Tape-stripping is a minimally invasive approach for skin sampling that captures the cutaneous immune/barrier abnormalities in atopic dermatitis (AD). However, tape-strips have not been used to evaluate molecular changes with therapeutic targeting. In this study, we sought to characterize the proteom...

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Bibliographic Details
Main Authors: Helen He, Caroline M. Olesen, Ana B. Pavel, Maja-Lisa Clausen, Jianni Wu, Yeriel Estrada, Ning Zhang, Tove Agner, Emma Guttman-Yassky
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
atopic dermatitis
dupilumab
tape-strips
olink
proteomics
targeted therapeutics
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01768/full

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