Reducing the receipt of contraindicated medications in patients with Parkinson disease
BackgroundThe administration of antidopaminergic medications to patients with Parkinson’s disease (PD) can exacerbate symptoms, and in the hospital setting, can lead to complications and increased length of stay. Despite efforts to improve medication administration through provider education and pat...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1271072/full |
| _version_ | 1827794678869655552 |
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| author | Caroline Goldin Stefan Sillau Elisa Worledge Jarrett Bremmer Robbie Cummins Kathryn Tremolet de Villers Michelle E. Fullard |
| author_facet | Caroline Goldin Stefan Sillau Elisa Worledge Jarrett Bremmer Robbie Cummins Kathryn Tremolet de Villers Michelle E. Fullard |
| author_sort | Caroline Goldin |
| collection | DOAJ |
| description | BackgroundThe administration of antidopaminergic medications to patients with Parkinson’s disease (PD) can exacerbate symptoms, and in the hospital setting, can lead to complications and increased length of stay. Despite efforts to improve medication administration through provider education and patient-centered interventions, the problem persists, with an estimated 21–43% of hospitalized PD patients receiving dopamine blocking medications.MethodsIn this study, a best practice alert (BPA) was developed that was triggered when an antidopaminergic medication was ordered in the Emergency Department or hospital for a patient with a diagnosis of PD in the EMR. The primary outcomes were receipt of a contraindicated medication, length of stay (LOS) and readmission within 30 days. These outcomes were compared between the 12 months prior to the intervention and the 12 months post intervention. Data were also collected on admitting diagnosis, admitting service, neurology involvement and patient demographics.ResultsFor pre-intervention inpatient encounters, 18.3% involved the use of a contraindicated medication. This was reduced to 9.4% of all inpatient encounters for PD patients in the first 3 months post-intervention and remained lower at 13.3% for the full 12 months post-intervention. The overall rate of contraindicated medication use was low for ED visits at 4.7% pre-intervention and 5.7% post-intervention. Receipt of a contraindicated medication increased the risk of a longer length of stay, both before and after the intervention, but did not significantly affect 30-day readmission rate.ConclusionAn EMR BPA decreased the use of contraindicated medications for PD patients in the hospital setting, especially in the first 3 months. Strategies are still needed to reduce alert fatigue in order to maintain initial improvements. |
| first_indexed | 2024-03-11T18:38:16Z |
| format | Article |
| id | doaj.art-ddcdf3cefed7471ca708b46366b1be87 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-03-11T18:38:16Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-ddcdf3cefed7471ca708b46366b1be872023-10-12T16:31:17ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-10-011510.3389/fnagi.2023.12710721271072Reducing the receipt of contraindicated medications in patients with Parkinson diseaseCaroline Goldin0Stefan Sillau1Elisa Worledge2Jarrett Bremmer3Robbie Cummins4Kathryn Tremolet de Villers5Michelle E. Fullard6Department of Neurology, Ochsner Medical Center, New Orleans, LA, United StatesDepartment of Neurology, University of Colorado, Aurora, CO, United StatesUniversity of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Denver Health, Denver, CO, United StatesBaptist Health, Jacksonville, FL, United StatesDepartment of Neurology, University of Colorado, Aurora, CO, United StatesDepartment of Pharmacy, University of Colorado Hospital, Aurora, CO, United StatesDepartment of Neurology, University of Colorado, Aurora, CO, United StatesBackgroundThe administration of antidopaminergic medications to patients with Parkinson’s disease (PD) can exacerbate symptoms, and in the hospital setting, can lead to complications and increased length of stay. Despite efforts to improve medication administration through provider education and patient-centered interventions, the problem persists, with an estimated 21–43% of hospitalized PD patients receiving dopamine blocking medications.MethodsIn this study, a best practice alert (BPA) was developed that was triggered when an antidopaminergic medication was ordered in the Emergency Department or hospital for a patient with a diagnosis of PD in the EMR. The primary outcomes were receipt of a contraindicated medication, length of stay (LOS) and readmission within 30 days. These outcomes were compared between the 12 months prior to the intervention and the 12 months post intervention. Data were also collected on admitting diagnosis, admitting service, neurology involvement and patient demographics.ResultsFor pre-intervention inpatient encounters, 18.3% involved the use of a contraindicated medication. This was reduced to 9.4% of all inpatient encounters for PD patients in the first 3 months post-intervention and remained lower at 13.3% for the full 12 months post-intervention. The overall rate of contraindicated medication use was low for ED visits at 4.7% pre-intervention and 5.7% post-intervention. Receipt of a contraindicated medication increased the risk of a longer length of stay, both before and after the intervention, but did not significantly affect 30-day readmission rate.ConclusionAn EMR BPA decreased the use of contraindicated medications for PD patients in the hospital setting, especially in the first 3 months. Strategies are still needed to reduce alert fatigue in order to maintain initial improvements.https://www.frontiersin.org/articles/10.3389/fnagi.2023.1271072/fullParkinson ‘s diseasebest practice alertquality improvementelectronic medical recordcontraindicated medications |
| spellingShingle | Caroline Goldin Stefan Sillau Elisa Worledge Jarrett Bremmer Robbie Cummins Kathryn Tremolet de Villers Michelle E. Fullard Reducing the receipt of contraindicated medications in patients with Parkinson disease Frontiers in Aging Neuroscience Parkinson ‘s disease best practice alert quality improvement electronic medical record contraindicated medications |
| title | Reducing the receipt of contraindicated medications in patients with Parkinson disease |
| title_full | Reducing the receipt of contraindicated medications in patients with Parkinson disease |
| title_fullStr | Reducing the receipt of contraindicated medications in patients with Parkinson disease |
| title_full_unstemmed | Reducing the receipt of contraindicated medications in patients with Parkinson disease |
| title_short | Reducing the receipt of contraindicated medications in patients with Parkinson disease |
| title_sort | reducing the receipt of contraindicated medications in patients with parkinson disease |
| topic | Parkinson ‘s disease best practice alert quality improvement electronic medical record contraindicated medications |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1271072/full |
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