Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity
Inhibitors of intestinal enzymes regulate carbohydrate metabolism reducing glycemic index, glycemic load of food and postprandial glycemia which is a prognostic factor of DM2-related cardiovascular complications and death. This class of drugs was proposed for DM2 treatment in 1970s but still holds p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2011-05-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30879 |
| _version_ | 1818963854076411904 |
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| author | Aleksandr Sergeevich Ametov Lyudmila Leonidovna Kamynina A S Ametov L L Kamynina |
| author_facet | Aleksandr Sergeevich Ametov Lyudmila Leonidovna Kamynina A S Ametov L L Kamynina |
| author_sort | Aleksandr Sergeevich Ametov |
| collection | DOAJ |
| description | Inhibitors of intestinal enzymes regulate carbohydrate metabolism reducing glycemic index, glycemic load of food and postprandial glycemia which is a prognostic factor of DM2-related cardiovascular complications and death. This class of drugs was proposed for DM2 treatment in 1970s but still holds perspectives. The article gives a detailed description of the mechanism of action, efficacy and safety of inhibitors of alpha-glucosidase and alpha-amilase in experimental and clinical controlled trials. |
| first_indexed | 2024-12-20T12:51:50Z |
| format | Article |
| id | doaj.art-ddd46f81db414629ab102b4429c1e581 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-20T12:51:50Z |
| publishDate | 2011-05-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-ddd46f81db414629ab102b4429c1e5812022-12-21T19:40:09Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422011-05-01835768027895Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesityAleksandr Sergeevich AmetovLyudmila Leonidovna KamyninaA S Ametov0L L Kamynina1Russian Medical Academy of Postgraduate Education, MoscowRussian Medical Academy of Postgraduate Education, MoscowInhibitors of intestinal enzymes regulate carbohydrate metabolism reducing glycemic index, glycemic load of food and postprandial glycemia which is a prognostic factor of DM2-related cardiovascular complications and death. This class of drugs was proposed for DM2 treatment in 1970s but still holds perspectives. The article gives a detailed description of the mechanism of action, efficacy and safety of inhibitors of alpha-glucosidase and alpha-amilase in experimental and clinical controlled trials.https://ter-arkhiv.ru/0040-3660/article/view/30879type 2 diabetes mellitusvisceral obesityalpha-glucosidase inhibitorsinhibitors of alpha-amilase |
| spellingShingle | Aleksandr Sergeevich Ametov Lyudmila Leonidovna Kamynina A S Ametov L L Kamynina Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity Терапевтический архив type 2 diabetes mellitus visceral obesity alpha-glucosidase inhibitors inhibitors of alpha-amilase |
| title | Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity |
| title_full | Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity |
| title_fullStr | Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity |
| title_full_unstemmed | Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity |
| title_short | Efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and/or visceral obesity |
| title_sort | efficacy of pharmacological inhibition of intestinal saccharases in patients with diabetes mellitus type 2 and or visceral obesity |
| topic | type 2 diabetes mellitus visceral obesity alpha-glucosidase inhibitors inhibitors of alpha-amilase |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30879 |
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