Single-cell RNA datasets and bulk RNA datasets analysis demonstrated C1Q+ tumor-associated macrophage as a major and antitumor immune cell population in osteosarcoma

Single-cell RNA datasets and bulk RNA datasets analysis demonstrated C1Q+ tumor-associated macrophage as a major and antitumor immune cell population in osteosarcoma

BackgroundOsteosarcoma is the most frequent primary bone tumor with a poor prognosis. Immune infiltration proved to have a strong impact on prognosis. We analyzed single-cell datasets and bulk datasets to confirm the main immune cell populations and their properties in osteosarcoma.MethodsThe exampl...

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Bibliographic Details
Main Authors: Jihao Tu, Duo Wang, XiaoTian Zheng, Bin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
tumor-associated macrophages
osteosarcoma
immune infiltration
biomarker
single-cell sequencing technology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.911368/full

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