Systems engineering of Escherichia coli for high-level glutarate production from glucose

Systems engineering of Escherichia coli for high-level glutarate production from glucose

Abstract Glutarate is a key monomer in polyester and polyamide production. The low efficiency of the current biosynthetic pathways hampers its production by microbial cell factories. Herein, through metabolic simulation, a lysine-overproducing E. coli strain Lys5 is engineered, achieving titer, yiel...

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Bibliographic Details
Main Authors:	Zhilan Zhang, Ruyin Chu, Wanqing Wei, Wei Song, Chao Ye, Xiulai Chen, Jing Wu, Liming Liu, Cong Gao
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-024-45448-z

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