An Observational Study from Long-Term AAV Re-administration in Two Hemophilia Dogs

An Observational Study from Long-Term AAV Re-administration in Two Hemophilia Dogs

Adeno-associated virus (AAV) vectors have been successfully applied in hemophilia clinical trials. However, this approach is limited to patients without AAV-neutralizing antibodies (NAbs). In this study, we explored the feasibility of AAV re-administration in hemophilia A dogs treated initially 8 ye...

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Bibliographic Details
Main Authors: Junjiang Sun, Wenwei Shao, Xiaojing Chen, Elizabeth P. Merricks, Lauren Wimsey, Yasmina L. Abajas, Glenn P. Niemeyer, Clinton D. Lothrop, Paul E. Monahan, R. Jude Samulski, Timothy C. Nichols, Chengwen Li
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050118300755

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