Cadmium induces testosterone synthesis disorder by testicular cell damage via TLR4/MAPK/NF-κB signaling pathway leading to reduced sexual behavior in piglets

Cadmium induces testosterone synthesis disorder by testicular cell damage via TLR4/MAPK/NF-κB signaling pathway leading to reduced sexual behavior in piglets

Cadmium (Cd) is a highly toxic metal pollutant that can endanger the life and health of animals. Toll-like receptor 4 (TLR4) can result in testicular cell damage by positively regulating mitogen-activated protein kinase (MAPK)/nuclear factor-kappaB (NF-κB) signaling pathway. Meanwhile, Testosterone...

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Bibliographic Details
Main Authors: Yulong Li, Yue Zhang, Rui Feng, Peng Zheng, He Huang, Sitong Zhou, Wenbo Ji, Fushuo Huang, Honggui Liu, Guixue Zhang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
TLR4/MAPK/NF-κB signaling pathway
Testicular cell damage
Testosterone
Sexual behavior
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322001853

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