Poly-<i>α</i>, <i>β</i>-<i><span style="font-variant: small-caps">d</span></i>, <i><span style="font-variant: small-caps">l</span></i>-Aspartyl-Arg-Gly-Asp-Ser-Based Urokinase Nanoparticles for Thrombolysis Therapy

Poly-<i>α</i>, <i>β</i>-<i><span style="font-variant: small-caps">d</span></i>, <i><span style="font-variant: small-caps">l</span></i>-Aspartyl-Arg-Gly-Asp-Ser-Based Urokinase Nanoparticles for Thrombolysis Therapy

The most concerning adverse effects of thrombolytic agents are major bleeding and intracranial hemorrhage due to their short half-life, low fibrin specificity, and high dosage. To alleviate bleeding side effects during thrombolytic therapy which would bring about the risk of aggravation, we try to f...

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Bibliographic Details
Main Authors: Shuangling Chen, Meng Liang, Chengli Wu, Xiaoyi Zhang, Yuji Wang, Ming Zhao
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
urokinase
thrombolytic
targeted
nano delivery system
RGDS
Online Access:https://www.mdpi.com/1420-3049/28/6/2578

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