ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA
Background. Senna italica Miller or Cassia italica (Miller) Sprengel is a native medicinal plant growing in south of Iran and has laxative and cathartic effects. Anthraquinone compounds have been partly associated with the purgative effects of the plant. One of the side effects of anthraquinones is...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2000-12-01
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| Series: | Journal of Research in Medical Sciences |
| Subjects: | |
| Online Access: | http://journals.mui.ac.ir/jrms/article/view/3541 |
| _version_ | 1818806020766433280 |
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| author | A.R GHANADI N.A GHASEMI DEHKORDI M.J SOHRABI |
| author_facet | A.R GHANADI N.A GHASEMI DEHKORDI M.J SOHRABI |
| author_sort | A.R GHANADI |
| collection | DOAJ |
| description | Background. Senna italica Miller or Cassia italica (Miller) Sprengel is a native medicinal plant growing in south of Iran and has laxative and cathartic effects. Anthraquinone compounds have been partly associated with the purgative effects of the plant. One of the side effects of anthraquinones is griping and presence of flavonoid compounds in the plant may decrease this effect. Methods. In this study, the plant after being collected, was extracted by a soxhlet method. The isolation of flavonoids was carried out by means of preparative Thin Layer Chromatography of extract of the plant leaves. The structure of flavonoids was determined by the UV-Vis. techniques in methanol and by addition of the shift reagents and hydrolysis. The quantitative determinations of flavonoids in plant were also performed using an UV-Vis. spectroscopy method. Results and Discussion. Rutin or 5, 7, 3', 4' tetrahydroxy-flavone 3-O-rhamnoglucoside and two flavonoids from aurone group were isolated and identified from the leaves of Senna italica. The percent of flavonoids in Iranian Senna determined 1.5 fold than Cassia angustifolia. These flavonoids may decrease the griping effects of Senna anthraquinones |
| first_indexed | 2024-12-18T19:03:08Z |
| format | Article |
| id | doaj.art-dddbe10624b04801bf5cf6a94b88fb54 |
| institution | Directory Open Access Journal |
| issn | 1735-1995 1735-7136 |
| language | English |
| last_indexed | 2024-12-18T19:03:08Z |
| publishDate | 2000-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Medical Sciences |
| spelling | doaj.art-dddbe10624b04801bf5cf6a94b88fb542022-12-21T20:56:29ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362000-12-0154ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNAA.R GHANADIN.A GHASEMI DEHKORDIM.J SOHRABIBackground. Senna italica Miller or Cassia italica (Miller) Sprengel is a native medicinal plant growing in south of Iran and has laxative and cathartic effects. Anthraquinone compounds have been partly associated with the purgative effects of the plant. One of the side effects of anthraquinones is griping and presence of flavonoid compounds in the plant may decrease this effect. Methods. In this study, the plant after being collected, was extracted by a soxhlet method. The isolation of flavonoids was carried out by means of preparative Thin Layer Chromatography of extract of the plant leaves. The structure of flavonoids was determined by the UV-Vis. techniques in methanol and by addition of the shift reagents and hydrolysis. The quantitative determinations of flavonoids in plant were also performed using an UV-Vis. spectroscopy method. Results and Discussion. Rutin or 5, 7, 3', 4' tetrahydroxy-flavone 3-O-rhamnoglucoside and two flavonoids from aurone group were isolated and identified from the leaves of Senna italica. The percent of flavonoids in Iranian Senna determined 1.5 fold than Cassia angustifolia. These flavonoids may decrease the griping effects of Senna anthraquinoneshttp://journals.mui.ac.ir/jrms/article/view/3541Senna (Cassia) italica, Leguminosae, Flavonoid, Rutin |
| spellingShingle | A.R GHANADI N.A GHASEMI DEHKORDI M.J SOHRABI ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA Journal of Research in Medical Sciences Senna (Cassia) italica, Leguminosae, Flavonoid, Rutin |
| title | ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA |
| title_full | ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA |
| title_fullStr | ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA |
| title_full_unstemmed | ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA |
| title_short | ISOLATION AND IDENTIFICATION OF FLAVONOIDS FROM IRANIAN SENNA |
| title_sort | isolation and identification of flavonoids from iranian senna |
| topic | Senna (Cassia) italica, Leguminosae, Flavonoid, Rutin |
| url | http://journals.mui.ac.ir/jrms/article/view/3541 |
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