Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against <i>Staphylococcus aureus</i> RnpA

Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against <i>Staphylococcus aureus</i> RnpA

<i>Staphylococcus aureus</i> is well-recognized to cause debilitating bacterial infections that are difficult to treat due to the emergence of antibiotic resistance. As such, there is a need to develop new antimicrobials for the therapeutic intervention of <i>S. aureus</i> di...

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Bibliographic Details
Main Authors: Michaelle Chojnacki, Xufeng Cao, Daniel P. Flaherty, Paul M. Dunman
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antibiotics
Subjects:
<i>Staphylococcus aureus</i>
antibiotic
RnpA
mRNA degradation
ptRNA processing
Online Access:https://www.mdpi.com/2079-6382/10/4/369

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