Parkin enhances sensitivity of paclitaxel to nasopharyngeal carcinoma by activating BNIP3/NIX-mediated mitochondrial autophagy

Parkin enhances sensitivity of paclitaxel to nasopharyngeal carcinoma by activating BNIP3/NIX-mediated mitochondrial autophagy

As a malignant head and neck cancer, nasopharyngeal carcinoma (NPC) has high morbidity. Parkin expression has been reported to be reduced in NPC tissues and its upregulation could enhance paclitaxel-resistant cell cycle arrest. This study was performed to explore the possible mechanism of Parkin rel...

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Bibliographic Details
Main Authors: Haifeng Ni, Renhui Liu, Zhen Zhou, Bo Jiang, Bin Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Chinese Journal of Physiology
Subjects:
bnip3/nix
mitochondrial autophagy
nasopharyngeal carcinoma
paclitaxel
parkin
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2023;volume=66;issue=6;spage=503;epage=515;aulast=Ni

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