Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures
Context : Blood stream infections are an important cause of mortality and morbidity. Enterococci have become increasingly resistant to a wide range of antimicrobial agents and enterococcal bacteraemia results in a high mortality of about 54%. Aim : The present study was done to determine the prev...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2012-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/2090/4263_E(C)_F(T)_PF(V)_PFA(A)_P(_).pdf |
| _version_ | 1818146462198923264 |
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| author | ANJANA TELKAR BARAGUNDI .MAHESH.C. RAGHAVENDRA V. P. VISHWANATH. G. CHANDRAPPA .N .R. |
| author_facet | ANJANA TELKAR BARAGUNDI .MAHESH.C. RAGHAVENDRA V. P. VISHWANATH. G. CHANDRAPPA .N .R. |
| author_sort | ANJANA TELKAR |
| collection | DOAJ |
| description | Context : Blood stream infections are an important cause of
mortality and morbidity. Enterococci have become increasingly
resistant to a wide range of antimicrobial agents and enterococcal bacteraemia results in a high mortality of about 54%.
Aim : The present study was done to determine the prevalence
of different enterococcal species in blood stream infections
and their anti-microbial resistance, with a special reference to
vancomycin and high level aminoglycoside resistance.
Material and methods : The study was conducted on 50 enterococcal blood isolates. The isolates were identified by using
standard microbiological techniques and antimicrobial susceptibility testing was done by the Kirby Bauer disc diffusion
method according to the CLSI guidelines.
Results : The maximum numbers of enterococci were isolated
from male patients of the age group of 0-20 years. Most of
the enterococcal isolates (78%) were non-haemolytic and multidrug resistant. E.faecium (70%) was the predominant species
which was isolated. Linezolid showed good antienterococcal
activity. Vancomycin resistance was seen in 6 (12%) isolates
and high level aminoglycoside resistance was seen in 20 (40%)
isolates. The E.faecium isolates were more drug resistant than
the E.faecalis isolates.
Conclusion : Steps should be taken to regularly screen the
enterococcal isolates for vancomycin and high level aminoglycoside resistance and to treat the enterococcal infections effectively to limit the spread of multidrug resistant enterococcal
infections. |
| first_indexed | 2024-12-11T12:19:44Z |
| format | Article |
| id | doaj.art-dde5d64709ac4dcf8833328da0594705 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T12:19:44Z |
| publishDate | 2012-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-dde5d64709ac4dcf8833328da05947052022-12-22T01:07:34ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2012-05-0163405407Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood CulturesANJANA TELKAR0BARAGUNDI .MAHESH.C.1RAGHAVENDRA V. P.2VISHWANATH. G.3CHANDRAPPA .N .R.4Assistant Professor, Dept. of microbiology, J.J.M. Medical College, Davanagere Karnataka – Pin 577004, India.Associate Professor, Dept. of Microbiology, S.N. Medical College, Bagalkot, Karnataka, India.Assistant Professor, Dept. of Anatomy, J.J.M. Medical College, Davanagere, Karnataka, India.Professor, Dept. of Microbiology, J.J.M. Medical College, Davanagere, Karnataka, India.Professor, Dept. of Microbiology, J.J.M. Medical College, Davanagere, Karnataka, India.Context : Blood stream infections are an important cause of mortality and morbidity. Enterococci have become increasingly resistant to a wide range of antimicrobial agents and enterococcal bacteraemia results in a high mortality of about 54%. Aim : The present study was done to determine the prevalence of different enterococcal species in blood stream infections and their anti-microbial resistance, with a special reference to vancomycin and high level aminoglycoside resistance. Material and methods : The study was conducted on 50 enterococcal blood isolates. The isolates were identified by using standard microbiological techniques and antimicrobial susceptibility testing was done by the Kirby Bauer disc diffusion method according to the CLSI guidelines. Results : The maximum numbers of enterococci were isolated from male patients of the age group of 0-20 years. Most of the enterococcal isolates (78%) were non-haemolytic and multidrug resistant. E.faecium (70%) was the predominant species which was isolated. Linezolid showed good antienterococcal activity. Vancomycin resistance was seen in 6 (12%) isolates and high level aminoglycoside resistance was seen in 20 (40%) isolates. The E.faecium isolates were more drug resistant than the E.faecalis isolates. Conclusion : Steps should be taken to regularly screen the enterococcal isolates for vancomycin and high level aminoglycoside resistance and to treat the enterococcal infections effectively to limit the spread of multidrug resistant enterococcal infections.https://jcdr.net/articles/PDF/2090/4263_E(C)_F(T)_PF(V)_PFA(A)_P(_).pdfenterococcusvree.faeciumhigh level aminoglycoside resistanceenterococcal bacteremia. |
| spellingShingle | ANJANA TELKAR BARAGUNDI .MAHESH.C. RAGHAVENDRA V. P. VISHWANATH. G. CHANDRAPPA .N .R. Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures Journal of Clinical and Diagnostic Research enterococcus vre e.faecium high level aminoglycoside resistance enterococcal bacteremia. |
| title | Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures |
| title_full | Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures |
| title_fullStr | Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures |
| title_full_unstemmed | Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures |
| title_short | Change in the Prevalence and the Antibiotic Resistance of the Enterococcal Species Isolated from Blood Cultures |
| title_sort | change in the prevalence and the antibiotic resistance of the enterococcal species isolated from blood cultures |
| topic | enterococcus vre e.faecium high level aminoglycoside resistance enterococcal bacteremia. |
| url | https://jcdr.net/articles/PDF/2090/4263_E(C)_F(T)_PF(V)_PFA(A)_P(_).pdf |
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