Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells

Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells

<p>Abstract</p> <p>Background</p> <p>Chromosomal aberrations of <it>BCL11A </it>at 2p16.1 have been reported in a variety of B-cell malignancies and its deficiency in mice leads to a profound block in B-cell development.</p> <p>Results</p>...

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Main Authors: Staudt Louis M, Shaffer Arthur L, Stockwin Luke, Banham Alison H, Pulford Karen, Lee Baeck-Seung, Probst Loren, Niu Teresa, Wall Jason K, Ippolito Gregory C, Liu Hui, Das Chhaya, Dyer Martin JS, Tucker Philip W
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/18

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