Primary malignant melanoma of the female urethra: A case report
Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and...
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Format: | Article |
Language: | English |
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Elsevier
2021-01-01
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Series: | Urology Case Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S221444202030382X |
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author | Kazuhiro Watanabe Go Hasegawa Katsunori Kashima Yo Sato Noboru Hara Tsutomu Nishiyama |
author_facet | Kazuhiro Watanabe Go Hasegawa Katsunori Kashima Yo Sato Noboru Hara Tsutomu Nishiyama |
author_sort | Kazuhiro Watanabe |
collection | DOAJ |
description | Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and ileal conduit diversion. Histopathological findings were urethral malignant melanoma, pT3apN0M0 (stage IIA). Nine months after surgery, computed tomography revealed a local recurrence in the pelvis, the patient was treated with immunotherapy using combined nivolumab and ipilimumab; however, she did not respond to treatment and died 22 months following diagnosis. |
first_indexed | 2024-12-17T20:40:39Z |
format | Article |
id | doaj.art-ddeae4f249d74b85b7f2cdbc249d3b55 |
institution | Directory Open Access Journal |
issn | 2214-4420 |
language | English |
last_indexed | 2024-12-17T20:40:39Z |
publishDate | 2021-01-01 |
publisher | Elsevier |
record_format | Article |
series | Urology Case Reports |
spelling | doaj.art-ddeae4f249d74b85b7f2cdbc249d3b552022-12-21T21:33:20ZengElsevierUrology Case Reports2214-44202021-01-0134101493Primary malignant melanoma of the female urethra: A case reportKazuhiro Watanabe0Go Hasegawa1Katsunori Kashima2Yo Sato3Noboru Hara4Tsutomu Nishiyama5Department of Urology, JapanDepartment of Pathology, JapanDepartment of Gynecology, JapanDepartment of General Surgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, JapanDepartment of Urology, JapanDepartment of Urology, Japan; Corresponding author. Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Urasa 4132, Minamiuonumashi, 949Niigata, Japan.Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and ileal conduit diversion. Histopathological findings were urethral malignant melanoma, pT3apN0M0 (stage IIA). Nine months after surgery, computed tomography revealed a local recurrence in the pelvis, the patient was treated with immunotherapy using combined nivolumab and ipilimumab; however, she did not respond to treatment and died 22 months following diagnosis.http://www.sciencedirect.com/science/article/pii/S221444202030382XMalignant melanomaUrethraAnterior pelvic exenterationImmuno-oncology therapy |
spellingShingle | Kazuhiro Watanabe Go Hasegawa Katsunori Kashima Yo Sato Noboru Hara Tsutomu Nishiyama Primary malignant melanoma of the female urethra: A case report Urology Case Reports Malignant melanoma Urethra Anterior pelvic exenteration Immuno-oncology therapy |
title | Primary malignant melanoma of the female urethra: A case report |
title_full | Primary malignant melanoma of the female urethra: A case report |
title_fullStr | Primary malignant melanoma of the female urethra: A case report |
title_full_unstemmed | Primary malignant melanoma of the female urethra: A case report |
title_short | Primary malignant melanoma of the female urethra: A case report |
title_sort | primary malignant melanoma of the female urethra a case report |
topic | Malignant melanoma Urethra Anterior pelvic exenteration Immuno-oncology therapy |
url | http://www.sciencedirect.com/science/article/pii/S221444202030382X |
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