Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients
In this work, we aimed to develop an automatic algorithm for the quantification of total volume and lung impairments in four different diseases. The quantification was completely automatic based upon high resolution computed tomography exams. The algorithm was capable of measuring volume and differe...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191897/?tool=EBI |
| _version_ | 1798035146061905920 |
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| author | Allan Felipe Fattori Alves José Ricardo Arruda Miranda Fabiano Reis Abner Alves Oliveira Sérgio Augusto Santana Souza Carlos Magno Castelo Branco Fortaleza Suzana Erico Tanni José Thiago Souza Castro Diana Rodrigues Pina |
| author_facet | Allan Felipe Fattori Alves José Ricardo Arruda Miranda Fabiano Reis Abner Alves Oliveira Sérgio Augusto Santana Souza Carlos Magno Castelo Branco Fortaleza Suzana Erico Tanni José Thiago Souza Castro Diana Rodrigues Pina |
| author_sort | Allan Felipe Fattori Alves |
| collection | DOAJ |
| description | In this work, we aimed to develop an automatic algorithm for the quantification of total volume and lung impairments in four different diseases. The quantification was completely automatic based upon high resolution computed tomography exams. The algorithm was capable of measuring volume and differentiating pulmonary involvement including inflammatory process and fibrosis, emphysema, and ground-glass opacities. The algorithm classifies the percentage of each pulmonary involvement when compared to the entire lung volume. Our algorithm was applied to four different patients groups: no lung disease patients, patients diagnosed with SARS-CoV-2, patients with chronic obstructive pulmonary disease, and patients with paracoccidioidomycosis. The quantification results were compared with a semi-automatic algorithm previously validated. Results confirmed that the automatic approach has a good agreement with the semi-automatic. Bland-Altman (B&A) demonstrated a low dispersion when comparing total lung volume, and also when comparing each lung impairment individually. Linear regression adjustment achieved an R value of 0.81 when comparing total lung volume between both methods. Our approach provides a reliable quantification process for physicians, thus impairments measurements contributes to support prognostic decisions in important lung diseases including the infection of SARS-CoV-2. |
| first_indexed | 2024-04-11T20:54:11Z |
| format | Article |
| id | doaj.art-ddebe0dd5ba347c88d23aa8b695819a4 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-11T20:54:11Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ddebe0dd5ba347c88d23aa8b695819a42022-12-22T04:03:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01166Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patientsAllan Felipe Fattori AlvesJosé Ricardo Arruda MirandaFabiano ReisAbner Alves OliveiraSérgio Augusto Santana SouzaCarlos Magno Castelo Branco FortalezaSuzana Erico TanniJosé Thiago Souza CastroDiana Rodrigues PinaIn this work, we aimed to develop an automatic algorithm for the quantification of total volume and lung impairments in four different diseases. The quantification was completely automatic based upon high resolution computed tomography exams. The algorithm was capable of measuring volume and differentiating pulmonary involvement including inflammatory process and fibrosis, emphysema, and ground-glass opacities. The algorithm classifies the percentage of each pulmonary involvement when compared to the entire lung volume. Our algorithm was applied to four different patients groups: no lung disease patients, patients diagnosed with SARS-CoV-2, patients with chronic obstructive pulmonary disease, and patients with paracoccidioidomycosis. The quantification results were compared with a semi-automatic algorithm previously validated. Results confirmed that the automatic approach has a good agreement with the semi-automatic. Bland-Altman (B&A) demonstrated a low dispersion when comparing total lung volume, and also when comparing each lung impairment individually. Linear regression adjustment achieved an R value of 0.81 when comparing total lung volume between both methods. Our approach provides a reliable quantification process for physicians, thus impairments measurements contributes to support prognostic decisions in important lung diseases including the infection of SARS-CoV-2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191897/?tool=EBI |
| spellingShingle | Allan Felipe Fattori Alves José Ricardo Arruda Miranda Fabiano Reis Abner Alves Oliveira Sérgio Augusto Santana Souza Carlos Magno Castelo Branco Fortaleza Suzana Erico Tanni José Thiago Souza Castro Diana Rodrigues Pina Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients PLoS ONE |
| title | Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients |
| title_full | Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients |
| title_fullStr | Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients |
| title_full_unstemmed | Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients |
| title_short | Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients |
| title_sort | automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease infection with sars cov 2 paracoccidioidomycosis and no lung disease patients |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191897/?tool=EBI |
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