Rapamycin and bafilomycin A1 alter autophagy and megakaryopoiesis

Rapamycin and bafilomycin A1 alter autophagy and megakaryopoiesis

Autophagy is an effective strategy for cell development by recycling cytoplasmic constituents. Genetic deletion of autophagy mediator Atg7 in hematopoietic stem cells (HSCs) can lead to failure of megakaryopoiesis and enhanced autophagy has been implicated in various hematological disorders such as...

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Bibliographic Details
Main Authors: Qi Wang, Tao You, Hongqiong Fan, Yinyan Wang, Tinatian Chu, Mortimer Poncz, Li Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Platelets
Subjects:
autophagy
megakaryopoiesis
thrombopoiesis
Online Access:http://dx.doi.org/10.1080/09537104.2016.1204436

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