Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector
<abstract language="eng">The aim of this study was to validate a method for the determination of acethaldehyde, methanol, ethanol, acetone and isopropanol employing solid-phase microextraction associated to gas chromatography with flame ionization detection. The operational condition...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2009-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000900031 |
| _version_ | 1818893786932051968 |
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| author | Lílian de Lima Feltraco Marina Venzon Antunes Rafael Linden |
| author_facet | Lílian de Lima Feltraco Marina Venzon Antunes Rafael Linden |
| author_sort | Lílian de Lima Feltraco |
| collection | DOAJ |
| description | <abstract language="eng">The aim of this study was to validate a method for the determination of acethaldehyde, methanol, ethanol, acetone and isopropanol employing solid-phase microextraction associated to gas chromatography with flame ionization detection. The operational conditions of SPME were optimized by response surface analysis. The calibration curves for all compounds were linear with r² > 0.9973. Accuracy (89.1-109.0%), intra-assay precision (1.8-8.5%) and inter-assay precision (2.2-8.2%) were acceptable. The quantification limit was 50 µg/mL. The method was applied to the meaurement of ethanol in blood and oral fluid of a group of volunteers. Oral fluid ethanol concentrations were not directly correlated with blood concentrations. |
| first_indexed | 2024-12-19T18:18:08Z |
| format | Article |
| id | doaj.art-ddf06946ed34410aa2d232979af56f08 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-19T18:18:08Z |
| publishDate | 2009-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-ddf06946ed34410aa2d232979af56f082022-12-21T20:11:04ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642009-01-013292401240610.1590/S0100-40422009000900031Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detectorLílian de Lima FeltracoMarina Venzon AntunesRafael Linden<abstract language="eng">The aim of this study was to validate a method for the determination of acethaldehyde, methanol, ethanol, acetone and isopropanol employing solid-phase microextraction associated to gas chromatography with flame ionization detection. The operational conditions of SPME were optimized by response surface analysis. The calibration curves for all compounds were linear with r² > 0.9973. Accuracy (89.1-109.0%), intra-assay precision (1.8-8.5%) and inter-assay precision (2.2-8.2%) were acceptable. The quantification limit was 50 µg/mL. The method was applied to the meaurement of ethanol in blood and oral fluid of a group of volunteers. Oral fluid ethanol concentrations were not directly correlated with blood concentrations.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000900031ethanolSPME-GC-FIDoral fluid |
| spellingShingle | Lílian de Lima Feltraco Marina Venzon Antunes Rafael Linden Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector Química Nova ethanol SPME-GC-FID oral fluid |
| title | Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector |
| title_full | Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector |
| title_fullStr | Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector |
| title_full_unstemmed | Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector |
| title_short | Determinação de etanol e voláteis relacionados em sangue e fluido oral por microextração em fase sólida em headspace associada à cromatografia gasosa com detector de ionização em chama Determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid-phase micro extraction associated to gas chromatography with flame-ionization detector |
| title_sort | determinacao de etanol e volateis relacionados em sangue e fluido oral por microextracao em fase solida em headspace associada a cromatografia gasosa com detector de ionizacao em chama determination of ethanol and related volatile compounds in blood and oral fluid by headspace solid phase micro extraction associated to gas chromatography with flame ionization detector |
| topic | ethanol SPME-GC-FID oral fluid |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000900031 |
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