Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria

Pituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most com...

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Main Authors: Ibrahim Alali, Alaa Al-Sarraj, Younes Kabalan
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2023/1482675
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author Ibrahim Alali
Alaa Al-Sarraj
Younes Kabalan
author_facet Ibrahim Alali
Alaa Al-Sarraj
Younes Kabalan
author_sort Ibrahim Alali
collection DOAJ
description Pituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most common cancers associated with PM. Despite advances in diagnostic and therapeutic options, the prognosis remains poor and is influenced by primary malignancy and treatment methods. We report a case of a patient with PM from lung cancer who had polyuria, polydipsia, and nonspecific symptoms. A full evaluation confirmed central diabetes insipidus, hypogonadism, and metastatic lung cancer. We also discuss the current literature on PM diagnosis and management, emphasizing the need for a comprehensive evaluation of all available data. This is the first case of PM reported from Syria, to our knowledge.
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spelling doaj.art-ddf46fd7b38445dab5ed15e5407e734e2023-09-20T00:00:02ZengHindawi LimitedCase Reports in Endocrinology2090-651X2023-01-01202310.1155/2023/1482675Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from SyriaIbrahim Alali0Alaa Al-Sarraj1Younes Kabalan2Endocrinology DepartmentEndocrinology DepartmentEndocrinology DepartmentPituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most common cancers associated with PM. Despite advances in diagnostic and therapeutic options, the prognosis remains poor and is influenced by primary malignancy and treatment methods. We report a case of a patient with PM from lung cancer who had polyuria, polydipsia, and nonspecific symptoms. A full evaluation confirmed central diabetes insipidus, hypogonadism, and metastatic lung cancer. We also discuss the current literature on PM diagnosis and management, emphasizing the need for a comprehensive evaluation of all available data. This is the first case of PM reported from Syria, to our knowledge.http://dx.doi.org/10.1155/2023/1482675
spellingShingle Ibrahim Alali
Alaa Al-Sarraj
Younes Kabalan
Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
Case Reports in Endocrinology
title Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
title_full Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
title_fullStr Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
title_full_unstemmed Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
title_short Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
title_sort diabetes insipidus due to metastases of undiagnosed lung cancer a case report from syria
url http://dx.doi.org/10.1155/2023/1482675
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AT alaaalsarraj diabetesinsipidusduetometastasesofundiagnosedlungcanceracasereportfromsyria
AT youneskabalan diabetesinsipidusduetometastasesofundiagnosedlungcanceracasereportfromsyria