Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria
Pituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most com...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Hindawi Limited
2023-01-01
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Series: | Case Reports in Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2023/1482675 |
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author | Ibrahim Alali Alaa Al-Sarraj Younes Kabalan |
author_facet | Ibrahim Alali Alaa Al-Sarraj Younes Kabalan |
author_sort | Ibrahim Alali |
collection | DOAJ |
description | Pituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most common cancers associated with PM. Despite advances in diagnostic and therapeutic options, the prognosis remains poor and is influenced by primary malignancy and treatment methods. We report a case of a patient with PM from lung cancer who had polyuria, polydipsia, and nonspecific symptoms. A full evaluation confirmed central diabetes insipidus, hypogonadism, and metastatic lung cancer. We also discuss the current literature on PM diagnosis and management, emphasizing the need for a comprehensive evaluation of all available data. This is the first case of PM reported from Syria, to our knowledge. |
first_indexed | 2024-03-11T23:36:24Z |
format | Article |
id | doaj.art-ddf46fd7b38445dab5ed15e5407e734e |
institution | Directory Open Access Journal |
issn | 2090-651X |
language | English |
last_indexed | 2024-03-11T23:36:24Z |
publishDate | 2023-01-01 |
publisher | Hindawi Limited |
record_format | Article |
series | Case Reports in Endocrinology |
spelling | doaj.art-ddf46fd7b38445dab5ed15e5407e734e2023-09-20T00:00:02ZengHindawi LimitedCase Reports in Endocrinology2090-651X2023-01-01202310.1155/2023/1482675Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from SyriaIbrahim Alali0Alaa Al-Sarraj1Younes Kabalan2Endocrinology DepartmentEndocrinology DepartmentEndocrinology DepartmentPituitary metastases (PM) are extremely uncommon, accounting for less than 1% of all intracranial metastases. PM of an undiagnosed malignancy can commonly present with symptoms of hormonal deficiencies, central diabetes insipidus, and/or visual symptoms. Lung and breast malignancies are the most common cancers associated with PM. Despite advances in diagnostic and therapeutic options, the prognosis remains poor and is influenced by primary malignancy and treatment methods. We report a case of a patient with PM from lung cancer who had polyuria, polydipsia, and nonspecific symptoms. A full evaluation confirmed central diabetes insipidus, hypogonadism, and metastatic lung cancer. We also discuss the current literature on PM diagnosis and management, emphasizing the need for a comprehensive evaluation of all available data. This is the first case of PM reported from Syria, to our knowledge.http://dx.doi.org/10.1155/2023/1482675 |
spellingShingle | Ibrahim Alali Alaa Al-Sarraj Younes Kabalan Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria Case Reports in Endocrinology |
title | Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria |
title_full | Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria |
title_fullStr | Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria |
title_full_unstemmed | Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria |
title_short | Diabetes Insipidus due to Metastases of Undiagnosed Lung Cancer: A Case Report from Syria |
title_sort | diabetes insipidus due to metastases of undiagnosed lung cancer a case report from syria |
url | http://dx.doi.org/10.1155/2023/1482675 |
work_keys_str_mv | AT ibrahimalali diabetesinsipidusduetometastasesofundiagnosedlungcanceracasereportfromsyria AT alaaalsarraj diabetesinsipidusduetometastasesofundiagnosedlungcanceracasereportfromsyria AT youneskabalan diabetesinsipidusduetometastasesofundiagnosedlungcanceracasereportfromsyria |