Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma

Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma

<i>Background</i>: Malignant pleural mesothelioma (MPM) is driven by the inactivation of tumor suppressor genes (TSGs). An unmet need in the field is the translation of the genomic landscape into effective TSG-specific therapies. <i>Methods</i>: We correlated genomes against...

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Bibliographic Details
Main Authors: Haitang Yang, Duo Xu, Zhang Yang, Feng Yao, Heng Zhao, Ralph A. Schmid, Ren-Wang Peng
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
mesothelioma
tumor suppressor
targeted therapy
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/12/8/2310

Internet

https://www.mdpi.com/2072-6694/12/8/2310

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