Mucus threads from surface goblet cells clear particles from the airways

Mucus threads from surface goblet cells clear particles from the airways

Abstract Background The mucociliary clearance system driven by beating cilia protects the airways from inhaled microbes and particles. Large particles are cleared by mucus bundles made in submucosal glands by parallel linear polymers of the MUC5B mucins. However, the structural organization and func...

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Bibliographic Details
Main Authors: Anna Ermund, Lauren N. Meiss, Brendan Dolan, Florian Jaudas, Lars Ewaldsson, Andrea Bähr, Nikolai Klymiuk, Gunnar C. Hansson
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Respiratory Research
Subjects:
Mucins
Respiratory tract
Mucus bundle
Goblet cells
Trachea
Bronchi
Online Access:https://doi.org/10.1186/s12931-021-01898-3

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