Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2

Abstract Novel coronavirus 19 (COVID‐19) is the latest and most intense epidemic, which is caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). In addition to causing respiratory symptoms, SARS‐CoV‐2 can have severe effects on the nervous system. Clinically, COVID‐19 patients...

Full description

Bibliographic Details
Main Authors: Mei‐Fang Xiao, Zhi‐Jian You, Chang Zeng, Ze‐Bing Huang, Liang Dong
Format: Article
Language:English
Published: Wiley-VCH 2021-12-01
Series:Ibrain
Subjects:
Online Access:https://doi.org/10.1002/ibra.12008
_version_ 1811328370136317952
author Mei‐Fang Xiao
Zhi‐Jian You
Chang Zeng
Ze‐Bing Huang
Liang Dong
author_facet Mei‐Fang Xiao
Zhi‐Jian You
Chang Zeng
Ze‐Bing Huang
Liang Dong
author_sort Mei‐Fang Xiao
collection DOAJ
description Abstract Novel coronavirus 19 (COVID‐19) is the latest and most intense epidemic, which is caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). In addition to causing respiratory symptoms, SARS‐CoV‐2 can have severe effects on the nervous system. Clinically, COVID‐19 patients have been reported ranging from mild hypogeusia and hyposmia to severe neurological disorders, such as encephalopathy, encephalitis, strokes, and seizures syndrome. However, the pathological mechanisms of this SARS‐CoV‐2 neuro aggressiveness remain unclear, so it is of great significance to explore the neurological effects of SARS‐CoV‐2 infection. To facilitate clinicians to timely recognize the manifestations of COVID‐19 patients with neurological injury and timely treatment, the author hereby reviews the latest research progress in the possible pathways, clinical manifestations, and pathogenesis of COVID‐19 patients with nerve injury.
first_indexed 2024-04-13T15:24:57Z
format Article
id doaj.art-ddf84407266447b787c6ae807c283749
institution Directory Open Access Journal
issn 2769-2795
language English
last_indexed 2024-04-13T15:24:57Z
publishDate 2021-12-01
publisher Wiley-VCH
record_format Article
series Ibrain
spelling doaj.art-ddf84407266447b787c6ae807c2837492022-12-22T02:41:33ZengWiley-VCHIbrain2769-27952021-12-017435136110.1002/ibra.12008Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2Mei‐Fang Xiao0Zhi‐Jian You1Chang Zeng2Ze‐Bing Huang3Liang Dong4Health Management Center, Xiangya Hospital Central South University Changsha Hunan ChinaDepartment of Anesthesiology Liuzhou People's Hospital Affiliated to Guangxi Medical University Liuzhou Guangxi ChinaHealth Management Center, Xiangya Hospital Central South University Changsha Hunan ChinaDepartment of Infectious Diseases, Xiangya Hospital Central South University Changsha Hunan ChinaDepartment of Anesthesiology Liuzhou People's Hospital Affiliated to Guangxi Medical University Liuzhou Guangxi ChinaAbstract Novel coronavirus 19 (COVID‐19) is the latest and most intense epidemic, which is caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). In addition to causing respiratory symptoms, SARS‐CoV‐2 can have severe effects on the nervous system. Clinically, COVID‐19 patients have been reported ranging from mild hypogeusia and hyposmia to severe neurological disorders, such as encephalopathy, encephalitis, strokes, and seizures syndrome. However, the pathological mechanisms of this SARS‐CoV‐2 neuro aggressiveness remain unclear, so it is of great significance to explore the neurological effects of SARS‐CoV‐2 infection. To facilitate clinicians to timely recognize the manifestations of COVID‐19 patients with neurological injury and timely treatment, the author hereby reviews the latest research progress in the possible pathways, clinical manifestations, and pathogenesis of COVID‐19 patients with nerve injury.https://doi.org/10.1002/ibra.12008ACE‐2 receptorsCOVID‐19neurological symptomspathological mechanisms
spellingShingle Mei‐Fang Xiao
Zhi‐Jian You
Chang Zeng
Ze‐Bing Huang
Liang Dong
Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
Ibrain
ACE‐2 receptors
COVID‐19
neurological symptoms
pathological mechanisms
title Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
title_full Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
title_fullStr Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
title_full_unstemmed Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
title_short Update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus‐2
title_sort update on neurological symptoms in patients infected with severe acute respiratory syndrome coronavirus 2
topic ACE‐2 receptors
COVID‐19
neurological symptoms
pathological mechanisms
url https://doi.org/10.1002/ibra.12008
work_keys_str_mv AT meifangxiao updateonneurologicalsymptomsinpatientsinfectedwithsevereacuterespiratorysyndromecoronavirus2
AT zhijianyou updateonneurologicalsymptomsinpatientsinfectedwithsevereacuterespiratorysyndromecoronavirus2
AT changzeng updateonneurologicalsymptomsinpatientsinfectedwithsevereacuterespiratorysyndromecoronavirus2
AT zebinghuang updateonneurologicalsymptomsinpatientsinfectedwithsevereacuterespiratorysyndromecoronavirus2
AT liangdong updateonneurologicalsymptomsinpatientsinfectedwithsevereacuterespiratorysyndromecoronavirus2