Germline Variants in the POT1-Gene in High-Risk Melanoma Patients in Austria

Germline Variants in the POT1-Gene in High-Risk Melanoma Patients in Austria

Risk of melanoma is in part determined by genetic factors. Currently the only established high penetrance familial melanoma genes are CDKN2A and CDK4. Recent studies reported germline variants in POT1 in melanoma families. In the present study, we sequenced the entire POT1 gene in 694 patients from...

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Bibliographic Details
Main Authors: Christoph Müller, Milica Krunic, Judith Wendt, Arndt von Haeseler, Ichiro Okamoto
Format: Article
Language:English
Published: Oxford University Press 2018-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
POT1
melanoma
familial
genetics
Austria
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300394

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