Biosynthesis of melatonin from l-tryptophan by an engineered microbial cell factory

Biosynthesis of melatonin from l-tryptophan by an engineered microbial cell factory

Abstract Background The demand for melatonin is increasing due to its health-promoting bioactivities such as antioxidant and sleep benefits. Although melatonin is present in various organisms, its low content and high extraction cost make it unsustainable. Biosynthesis is a promising alternative met...

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Bibliographic Details
Main Authors: Lijuan Wang, Yongdong Deng, Jianjie Gao, Bo Wang, Hongjuan Han, Zhenjun Li, Wenhui Zhang, Yu Wang, Xiaoyan Fu, Rihe Peng, Quanhong Yao, Yongsheng Tian, Jing Xu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Biosynthesis
Melatonin
l-Tryptophan (l-Trp)
Escherichia coli
Metabolic engineering
Online Access:https://doi.org/10.1186/s13068-024-02476-7

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