Feasibility Assessment of a Biomarker-Guided Kidney-Sparing Sepsis Bundle: The Limiting Acute Kidney Injury Progression In Sepsis Trial

Feasibility Assessment of a Biomarker-Guided Kidney-Sparing Sepsis Bundle: The Limiting Acute Kidney Injury Progression In Sepsis Trial

OBJECTIVES:. To determine the feasibility, safety, and efficacy of a biomarker-guided implementation of a kidney-sparing sepsis bundle (KSSB) of care in comparison with standard of care (SOC) on clinical outcomes in patients with sepsis. DESIGN:. Adaptive, multicenter, randomized clinical trial. SET...

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Main Authors: Hernando Gómez, MD, Alexander Zarbock, MD, Stephen M. Pastores, MD, Gyorgy Frendl, MD, Sven Bercker, MD, Pierre Asfar, MD, Steven A. Conrad, MD, Jaques Creteur, MD, James Miner, MD, Jean Paul Mira, MD, Johan Motsch, MD, Jean-Pierre Quenot, MD, Thomas Rimmelé, MD, Peter Rosenberger, MD, Christophe Vinsonneau, MD, Bob Birch, PhD, Fabienne Heskia, MS, Julien Textoris, MD, Luca Molinari, MD, Louis M. Guzzi, MD, Claudio Ronco, MD, John A. Kellum, MD
Format: Article
Language:English
Published: Wolters Kluwer 2023-08-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000961

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