About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors
Total RNA isolated from peripheral blood lymphocytes of donor and patient with polycythemia, stimulates hematopoiesis in rats with toxic aplastic anemia due to benzene administration. Total RNA of lymphocytes from polycythemia patient has a more pronounced effect on the erythroid, myeloid and megaka...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-06-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/146 |
| _version_ | 1797855569790369792 |
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| author | A. G. Babaeva N. M. Gevorkyan N. V. Tishevskaya L. L. Golovkina Yu. O. Muratova A. A. Ragimov |
| author_facet | A. G. Babaeva N. M. Gevorkyan N. V. Tishevskaya L. L. Golovkina Yu. O. Muratova A. A. Ragimov |
| author_sort | A. G. Babaeva |
| collection | DOAJ |
| description | Total RNA isolated from peripheral blood lymphocytes of donor and patient with polycythemia, stimulates hematopoiesis in rats with toxic aplastic anemia due to benzene administration. Total RNA of lymphocytes from polycythemia patient has a more pronounced effect on the erythroid, myeloid and megakaryocytic hematopoiesis comparing to total RNA from donor lymphocytes. The greatest stimulatory effectof RNA observed after 21 days from the start of experiment. Total RNA of lymphocytes from polycythemia patient largely activates erythropoiesis promoting restoration of reticulocyte count in animals with aplastic anemia. |
| first_indexed | 2024-04-09T20:25:58Z |
| format | Article |
| id | doaj.art-de04e65e948145108a7b780c2e7d4a8a |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:25:58Z |
| publishDate | 2015-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-de04e65e948145108a7b780c2e7d4a8a2023-03-30T20:15:11ZrusABV-pressОнкогематология1818-83462413-40232015-06-01102586210.17650/1818-8346-2015-10-2-58-62161About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donorsA. G. Babaeva0N. M. Gevorkyan1N. V. Tishevskaya2L. L. Golovkina3Yu. O. Muratova4A. A. Ragimov5Research Institute of Human Morphology; 3 Tsyurupy St., Moscow, 117418, RussiaV. N. Orekhovich Institute of Biomedical Chemistry; 10, Bldg. 8 Pogodinskaya St., Moscow, 119121, RussiaSouth Ural State Medical University, Ministry of Health of Russia; 64 Vorovskogo St., Chelyabinsk, 454092, RussiaHematological Research Center, Ministry of Health of Russia; 4a Novyy Zykovskiy Pr-d, Moscow, 125167, RussiaHematological Research Center, Ministry of Health of Russia; 4a Novyy Zykovskiy Pr-d, Moscow, 125167, RussiaBlood Center, I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia; 2, Bldg. 4 Bolshaya Pirogovskaya St., Moscow, 119435, RussiaTotal RNA isolated from peripheral blood lymphocytes of donor and patient with polycythemia, stimulates hematopoiesis in rats with toxic aplastic anemia due to benzene administration. Total RNA of lymphocytes from polycythemia patient has a more pronounced effect on the erythroid, myeloid and megakaryocytic hematopoiesis comparing to total RNA from donor lymphocytes. The greatest stimulatory effectof RNA observed after 21 days from the start of experiment. Total RNA of lymphocytes from polycythemia patient largely activates erythropoiesis promoting restoration of reticulocyte count in animals with aplastic anemia.https://oncohematology.abvpress.ru/ongm/article/view/146hematopoiesiserythremiapolycythemia verapathogenesisperipheral blood lymphocytestotal rnahumanrat |
| spellingShingle | A. G. Babaeva N. M. Gevorkyan N. V. Tishevskaya L. L. Golovkina Yu. O. Muratova A. A. Ragimov About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors Онкогематология hematopoiesis erythremia polycythemia vera pathogenesis peripheral blood lymphocytes total rna human rat |
| title | About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors |
| title_full | About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors |
| title_fullStr | About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors |
| title_full_unstemmed | About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors |
| title_short | About hematopoietic properties of peripheral blood lymphocytes RNA from patients with polycythemia vera and healthy donors |
| title_sort | about hematopoietic properties of peripheral blood lymphocytes rna from patients with polycythemia vera and healthy donors |
| topic | hematopoiesis erythremia polycythemia vera pathogenesis peripheral blood lymphocytes total rna human rat |
| url | https://oncohematology.abvpress.ru/ongm/article/view/146 |
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