Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.

The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis. In this study, we carried out a fixed-load scratch experiment to compare the fr...

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Main Authors: Pai Zheng, Xueer Zhang, Chengcheng Feng, Yuhong Yu, Guangwei Che, Zhihong Cao, Li Tian, Yong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0298722
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author Pai Zheng
Xueer Zhang
Chengcheng Feng
Yuhong Yu
Guangwei Che
Zhihong Cao
Li Tian
Yong Huang
author_facet Pai Zheng
Xueer Zhang
Chengcheng Feng
Yuhong Yu
Guangwei Che
Zhihong Cao
Li Tian
Yong Huang
author_sort Pai Zheng
collection DOAJ
description The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis. In this study, we carried out a fixed-load scratch experiment to compare the friction and wear of articular cartilage under the lubrication of gouty arthritis arthritic fluid and normal human arthritic fluid, and the results showed that the cartilage friction coefficient of patients with acute gouty arthritis was significantly larger than that of normal human beings, and that the cartilage friction coefficient decreased with the elevation of normal load and sliding speed, and the change with the sliding speed varied more differently from that of normal human beings, and that the cartilage surface wear was more severe after prolonged friction. The wear and tear of the cartilage surface is more severe after prolonged friction. Patients with gouty arthritis should reduce the sudden speed changes such as fast running and variable speed running to maintain the stability of the cartilage surface friction coefficient.
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spelling doaj.art-de083985c7ba40828d5cb9b1211b278c2024-03-27T05:32:47ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01193e029872210.1371/journal.pone.0298722Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.Pai ZhengXueer ZhangChengcheng FengYuhong YuGuangwei CheZhihong CaoLi TianYong HuangThe tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis. In this study, we carried out a fixed-load scratch experiment to compare the friction and wear of articular cartilage under the lubrication of gouty arthritis arthritic fluid and normal human arthritic fluid, and the results showed that the cartilage friction coefficient of patients with acute gouty arthritis was significantly larger than that of normal human beings, and that the cartilage friction coefficient decreased with the elevation of normal load and sliding speed, and the change with the sliding speed varied more differently from that of normal human beings, and that the cartilage surface wear was more severe after prolonged friction. The wear and tear of the cartilage surface is more severe after prolonged friction. Patients with gouty arthritis should reduce the sudden speed changes such as fast running and variable speed running to maintain the stability of the cartilage surface friction coefficient.https://doi.org/10.1371/journal.pone.0298722
spellingShingle Pai Zheng
Xueer Zhang
Chengcheng Feng
Yuhong Yu
Guangwei Che
Zhihong Cao
Li Tian
Yong Huang
Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
PLoS ONE
title Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
title_full Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
title_fullStr Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
title_full_unstemmed Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
title_short Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.
title_sort alterations in articular cartilage frictional properties in the setting of acute gouty arthritis
url https://doi.org/10.1371/journal.pone.0298722
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