Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
Aim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine. Methods and results. The research work was carried out on 24 mature white male rats a...
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Format: | Article |
Language: | English |
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Zaporozhye State Medical University
2015-06-01
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Series: | Zaporožskij Medicinskij Žurnal |
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Online Access: | http://zmj.zsmu.edu.ua/article/view/44493/42749 |
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author | A. V. Zinko |
author_facet | A. V. Zinko |
author_sort | A. V. Zinko |
collection | DOAJ |
description | Aim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine.
Methods and results. The research work was carried out on 24 mature white male rats aged 3.0 – 4.5 months weighing 160-270 g. The method applied in the study was injection of bloodstream along with morphometric and statistical methods. Morphological and morphometric analysis of angioarchitecture of telencephalon radiate crown allowed to evaluate the degree of its vascularization in case of a long-term effect of nalbuphine.
Conclusion. Results showed that there is a clearly observed connection between the depth of structural transformations of the parts of hemomicrocirculatory bloodstream of the rat’s radiate crown under the influence of opioid and the morphometric indices. The obtained results can serve as the morphologic basis for further scientific research in neurology. |
first_indexed | 2024-12-22T15:30:59Z |
format | Article |
id | doaj.art-de09618e571d4e1f88af7a235709c476 |
institution | Directory Open Access Journal |
issn | 2306-4145 2310-1210 |
language | English |
last_indexed | 2024-12-22T15:30:59Z |
publishDate | 2015-06-01 |
publisher | Zaporozhye State Medical University |
record_format | Article |
series | Zaporožskij Medicinskij Žurnal |
spelling | doaj.art-de09618e571d4e1f88af7a235709c4762022-12-21T18:21:22ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102015-06-0137881http://dx.doi.org/10.14739/2310-1210.2015.3.44493Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid useA. V. ZinkoAim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine. Methods and results. The research work was carried out on 24 mature white male rats aged 3.0 – 4.5 months weighing 160-270 g. The method applied in the study was injection of bloodstream along with morphometric and statistical methods. Morphological and morphometric analysis of angioarchitecture of telencephalon radiate crown allowed to evaluate the degree of its vascularization in case of a long-term effect of nalbuphine. Conclusion. Results showed that there is a clearly observed connection between the depth of structural transformations of the parts of hemomicrocirculatory bloodstream of the rat’s radiate crown under the influence of opioid and the morphometric indices. The obtained results can serve as the morphologic basis for further scientific research in neurology.http://zmj.zsmu.edu.ua/article/view/44493/42749TelencephalonBlood VesselsRatsNalbuphine |
spellingShingle | A. V. Zinko Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use Zaporožskij Medicinskij Žurnal Telencephalon Blood Vessels Rats Nalbuphine |
title | Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use |
title_full | Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use |
title_fullStr | Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use |
title_full_unstemmed | Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use |
title_short | Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use |
title_sort | blood supply of the telencephalon radiate crown of the rat in norm and under the long term opioid use |
topic | Telencephalon Blood Vessels Rats Nalbuphine |
url | http://zmj.zsmu.edu.ua/article/view/44493/42749 |
work_keys_str_mv | AT avzinko bloodsupplyofthetelencephalonradiatecrownoftheratinnormandunderthelongtermopioiduse |