Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use

Aim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine. Methods and results. The research work was carried out on 24 mature white male rats a...

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Main Author: A. V. Zinko
Format: Article
Language:English
Published: Zaporozhye State Medical University 2015-06-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
Online Access:http://zmj.zsmu.edu.ua/article/view/44493/42749
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author A. V. Zinko
author_facet A. V. Zinko
author_sort A. V. Zinko
collection DOAJ
description Aim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine. Methods and results. The research work was carried out on 24 mature white male rats aged 3.0 – 4.5 months weighing 160-270 g. The method applied in the study was injection of bloodstream along with morphometric and statistical methods. Morphological and morphometric analysis of angioarchitecture of telencephalon radiate crown allowed to evaluate the degree of its vascularization in case of a long-term effect of nalbuphine. Conclusion. Results showed that there is a clearly observed connection between the depth of structural transformations of the parts of hemomicrocirculatory bloodstream of the rat’s radiate crown under the influence of opioid and the morphometric indices. The obtained results can serve as the morphologic basis for further scientific research in neurology.
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spelling doaj.art-de09618e571d4e1f88af7a235709c4762022-12-21T18:21:22ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102015-06-0137881http://dx.doi.org/10.14739/2310-1210.2015.3.44493Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid useA. V. ZinkoAim. The objective of this study was to establish peculiarities of the channels of blood supply of the telencephalon radiate crown of the rat in norm and in the dynamics in 6 weeks long injection of nalbuphine. Methods and results. The research work was carried out on 24 mature white male rats aged 3.0 – 4.5 months weighing 160-270 g. The method applied in the study was injection of bloodstream along with morphometric and statistical methods. Morphological and morphometric analysis of angioarchitecture of telencephalon radiate crown allowed to evaluate the degree of its vascularization in case of a long-term effect of nalbuphine. Conclusion. Results showed that there is a clearly observed connection between the depth of structural transformations of the parts of hemomicrocirculatory bloodstream of the rat’s radiate crown under the influence of opioid and the morphometric indices. The obtained results can serve as the morphologic basis for further scientific research in neurology.http://zmj.zsmu.edu.ua/article/view/44493/42749TelencephalonBlood VesselsRatsNalbuphine
spellingShingle A. V. Zinko
Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
Zaporožskij Medicinskij Žurnal
Telencephalon
Blood Vessels
Rats
Nalbuphine
title Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
title_full Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
title_fullStr Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
title_full_unstemmed Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
title_short Blood supply of the telencephalon radiate crown of the rat in norm and under the long-term opioid use
title_sort blood supply of the telencephalon radiate crown of the rat in norm and under the long term opioid use
topic Telencephalon
Blood Vessels
Rats
Nalbuphine
url http://zmj.zsmu.edu.ua/article/view/44493/42749
work_keys_str_mv AT avzinko bloodsupplyofthetelencephalonradiatecrownoftheratinnormandunderthelongtermopioiduse