Pluripotency markers are differentially induced by IGF1 and bFGF in cells from patients’ lesions of large/giant congenital melanocytic nevi

Pluripotency markers are differentially induced by IGF1 and bFGF in cells from patients’ lesions of large/giant congenital melanocytic nevi

Abstract Factors regulating transcription of pluripotency genes in congenital nevo-melanocytes are not known. Nevo-melanocytes belong somewhere in-between the ends of a spectrum where the normal epidermal melanocyte represents one end and a melanoma cell with multiple genetic abnormalities represent...

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Bibliographic Details
Main Authors: Dipanjan Basu, Cláudia M. Salgado, Janki R. Patel, Joie Zabec, Ryan M. Hoehl, Bruce Bauer, Miguel Reyes-Múgica
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Biomarker Research
Subjects:
Melanocytes
Giant congenital nevi
Melanoma
Online Access:http://link.springer.com/article/10.1186/s40364-018-0152-9

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