Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes

Objective: To investigate the clinical features, prescribing patterns and outcomes of psychiatric inpatients admitted with methamphetamine-induced psychosis. Method: A cross-sectional, descriptive pilot study was conducted between March 2014 and August 2014 at three South African Mental Health Care...

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Bibliografische gegevens
Hoofdauteurs: Eileen Thomas, Helena Lategan, Chris Verster, Martin Kidd, Lize Weich
Formaat: Artikel
Taal:English
Gepubliceerd in: AOSIS 2016-09-01
Reeks:South African Journal of Psychiatry
Onderwerpen:
Online toegang:http://www.sajp.org.za/index.php/sajp/article/view/980
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author Eileen Thomas
Helena Lategan
Chris Verster
Martin Kidd
Lize Weich
author_facet Eileen Thomas
Helena Lategan
Chris Verster
Martin Kidd
Lize Weich
author_sort Eileen Thomas
collection DOAJ
description Objective: To investigate the clinical features, prescribing patterns and outcomes of psychiatric inpatients admitted with methamphetamine-induced psychosis. Method: A cross-sectional, descriptive pilot study was conducted between March 2014 and August 2014 at three South African Mental Health Care Act designated hospitals prior to admission to a psychiatric hospital. Patients with methamphetamine-related psychotic symptoms according to the DSM-5 criteria were eligible. Structured face-to-face interviews were conducted and the Brief Psychiatric Rating Scale was employed as a measure of current psychopathology. Results: Fifty-six participants were included. Positive psychotic symptoms (e.g. hallucinations) were more prominent than negative symptoms (e.g. affective blunting). Almost half the participants (43%) had previous episodes of methamphetamine-induced psychosis. Within this group, all had defaulted on the prescribed treatment prior to admission. Only 29% of the participants had received prior formal substance-use rehabilitation as treatment for their disorder. High rates of comorbid cannabis and alcohol use (51%) were recorded. Most of the participants required transfer to specialist psychiatric hospitals. The amounts of methamphetamine used were not a predictor of the persistence of psychosis; however, the pattern of use was. Conclusion: Clinical features correspond with other international findings. The currently employed model of sequential, non-integrated psychiatric and substance use treatment in this setting appears ineffective.
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spelling doaj.art-de0ef6f0700142529e510fce3b901b0f2022-12-22T00:48:03ZengAOSISSouth African Journal of Psychiatry1608-96852078-67862016-09-01221e1e610.4102/sajpsychiatry.v22i1.980347Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomesEileen Thomas0Helena Lategan1Chris Verster2Martin Kidd3Lize Weich4Department of Psychiatry, Stellenbosch UniversityDepartment of Psychiatry, Stellenbosch UniversityDepartment of Psychiatry, Stellenbosch UniversityCentre for Statistical Consultation, Stellenbosch UniversityDepartment of Psychiatry, Stellenbosch UniversityObjective: To investigate the clinical features, prescribing patterns and outcomes of psychiatric inpatients admitted with methamphetamine-induced psychosis. Method: A cross-sectional, descriptive pilot study was conducted between March 2014 and August 2014 at three South African Mental Health Care Act designated hospitals prior to admission to a psychiatric hospital. Patients with methamphetamine-related psychotic symptoms according to the DSM-5 criteria were eligible. Structured face-to-face interviews were conducted and the Brief Psychiatric Rating Scale was employed as a measure of current psychopathology. Results: Fifty-six participants were included. Positive psychotic symptoms (e.g. hallucinations) were more prominent than negative symptoms (e.g. affective blunting). Almost half the participants (43%) had previous episodes of methamphetamine-induced psychosis. Within this group, all had defaulted on the prescribed treatment prior to admission. Only 29% of the participants had received prior formal substance-use rehabilitation as treatment for their disorder. High rates of comorbid cannabis and alcohol use (51%) were recorded. Most of the participants required transfer to specialist psychiatric hospitals. The amounts of methamphetamine used were not a predictor of the persistence of psychosis; however, the pattern of use was. Conclusion: Clinical features correspond with other international findings. The currently employed model of sequential, non-integrated psychiatric and substance use treatment in this setting appears ineffective.http://www.sajp.org.za/index.php/sajp/article/view/980MethamphetamineSouth AfricaPsychosisPhenomenology
spellingShingle Eileen Thomas
Helena Lategan
Chris Verster
Martin Kidd
Lize Weich
Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
South African Journal of Psychiatry
Methamphetamine
South Africa
Psychosis
Phenomenology
title Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
title_full Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
title_fullStr Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
title_full_unstemmed Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
title_short Methamphetamine-induced psychosis: Clinical features, treatment modalities and outcomes
title_sort methamphetamine induced psychosis clinical features treatment modalities and outcomes
topic Methamphetamine
South Africa
Psychosis
Phenomenology
url http://www.sajp.org.za/index.php/sajp/article/view/980
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AT martinkidd methamphetamineinducedpsychosisclinicalfeaturestreatmentmodalitiesandoutcomes
AT lizeweich methamphetamineinducedpsychosisclinicalfeaturestreatmentmodalitiesandoutcomes