Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations
Insufficient insulin secretion to meet metabolic demand results in diabetes. The intracellular flux of Ca2+ into β-cells triggers insulin release. Since genetics strongly influences variation in islet secretory responses, we surveyed islet Ca2+ dynamics in eight genetically diverse mouse strains. We...
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
eLife Sciences Publications Ltd
2023-10-01
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| श्रृंखला: | eLife |
| विषय: | |
| ऑनलाइन पहुंच: | https://elifesciences.org/articles/88189 |