Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure
Abstract Background Mastication is one of the most fundamental functions for the conservation of human life. To clarify the pathogenetic mechanism of various oral dysfunctions, the demand for devices for evaluating stomatognathic function has been increasing. The aim of the present study was to deve...
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| Format: | Article |
| Language: | English |
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BMC
2021-10-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-021-01879-4 |
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| author | Go Yasuda Emi Moriuchi Ryo Hamanaka Ayumi Fujishita Tomoko Yoshimi Kana Yamamoto Kaori Hayashida Yoshiyuki Koga Noriaki Yoshida |
| author_facet | Go Yasuda Emi Moriuchi Ryo Hamanaka Ayumi Fujishita Tomoko Yoshimi Kana Yamamoto Kaori Hayashida Yoshiyuki Koga Noriaki Yoshida |
| author_sort | Go Yasuda |
| collection | DOAJ |
| description | Abstract Background Mastication is one of the most fundamental functions for the conservation of human life. To clarify the pathogenetic mechanism of various oral dysfunctions, the demand for devices for evaluating stomatognathic function has been increasing. The aim of the present study was to develop a system to reconstruct and visualize 3-dimensional (3D) mandibular movements relative to the maxilla, including dynamic transition of occlusal contacts between the upper and lower dentitions during mastication in mice. Methods First, mandibular movements with six degrees of freedom were measured using a motion capture system comprising two high-speed cameras and four reflective markers. Second, 3D models of maxillofacial structure were reconstructed from micro-computed tomography images. Movement trajectories of anatomical landmark points on the mandible were then reproduced by integrating the kinematic data of mandibular movements with the anatomical data of maxillofacial structures. Lastly, 3D surface images of the upper dentition with the surrounding maxillofacial structures were transferred to each of the motion capture images to reproduce mandibular movements relative to the maxilla. We also performed electromyography (EMG) of masticatory muscles associated with mandibular movements. Results The developed system could reproduce the 3D movement trajectories of arbitrary points on the mandible, such as incisor, molars and condylar points with high accuracy and could visualize dynamic transitions of occlusal contacts between upper and lower teeth associated with mandibular movements. Conclusions The proposed system has potential to elucidate the mechanisms underlying motor coordination of masticatory muscles and to clarify their roles during mastication by taking advantage of the capability to record EMG data synchronously with mandibular movements. Such insights will enhance our understanding of the pathogenesis and diagnosis of oral motor disorders by allowing comparisons between normal mice and genetically modified mice with oral behavioral dysfunctions. |
| first_indexed | 2024-12-16T08:41:56Z |
| format | Article |
| id | doaj.art-de10ade4c601432db97c9d708d7bf67a |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-12-16T08:41:56Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-de10ade4c601432db97c9d708d7bf67a2022-12-21T22:37:40ZengBMCBMC Oral Health1472-68312021-10-0121111210.1186/s12903-021-01879-4Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structureGo Yasuda0Emi Moriuchi1Ryo Hamanaka2Ayumi Fujishita3Tomoko Yoshimi4Kana Yamamoto5Kaori Hayashida6Yoshiyuki Koga7Noriaki Yoshida8Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityDepartment of Orthodontics, Nagasaki University HospitalDepartment of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityDepartment of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityDepartment of Orthodontics, Nagasaki University HospitalDepartment of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityDepartment of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityDepartment of Orthodontics, Nagasaki University HospitalDepartment of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki UniversityAbstract Background Mastication is one of the most fundamental functions for the conservation of human life. To clarify the pathogenetic mechanism of various oral dysfunctions, the demand for devices for evaluating stomatognathic function has been increasing. The aim of the present study was to develop a system to reconstruct and visualize 3-dimensional (3D) mandibular movements relative to the maxilla, including dynamic transition of occlusal contacts between the upper and lower dentitions during mastication in mice. Methods First, mandibular movements with six degrees of freedom were measured using a motion capture system comprising two high-speed cameras and four reflective markers. Second, 3D models of maxillofacial structure were reconstructed from micro-computed tomography images. Movement trajectories of anatomical landmark points on the mandible were then reproduced by integrating the kinematic data of mandibular movements with the anatomical data of maxillofacial structures. Lastly, 3D surface images of the upper dentition with the surrounding maxillofacial structures were transferred to each of the motion capture images to reproduce mandibular movements relative to the maxilla. We also performed electromyography (EMG) of masticatory muscles associated with mandibular movements. Results The developed system could reproduce the 3D movement trajectories of arbitrary points on the mandible, such as incisor, molars and condylar points with high accuracy and could visualize dynamic transitions of occlusal contacts between upper and lower teeth associated with mandibular movements. Conclusions The proposed system has potential to elucidate the mechanisms underlying motor coordination of masticatory muscles and to clarify their roles during mastication by taking advantage of the capability to record EMG data synchronously with mandibular movements. Such insights will enhance our understanding of the pathogenesis and diagnosis of oral motor disorders by allowing comparisons between normal mice and genetically modified mice with oral behavioral dysfunctions.https://doi.org/10.1186/s12903-021-01879-4Motion captureJaw movementsMasticationMouseRigid transformationEMG |
| spellingShingle | Go Yasuda Emi Moriuchi Ryo Hamanaka Ayumi Fujishita Tomoko Yoshimi Kana Yamamoto Kaori Hayashida Yoshiyuki Koga Noriaki Yoshida Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure BMC Oral Health Motion capture Jaw movements Mastication Mouse Rigid transformation EMG |
| title | Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure |
| title_full | Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure |
| title_fullStr | Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure |
| title_full_unstemmed | Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure |
| title_short | Visualization of mandibular movement relative to the maxilla during mastication in mice: integration of kinematic analysis and reconstruction of a three-dimensional model of the maxillofacial structure |
| title_sort | visualization of mandibular movement relative to the maxilla during mastication in mice integration of kinematic analysis and reconstruction of a three dimensional model of the maxillofacial structure |
| topic | Motion capture Jaw movements Mastication Mouse Rigid transformation EMG |
| url | https://doi.org/10.1186/s12903-021-01879-4 |
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